Protein Alignment Hsc70-2 and SSE1

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_015219.1
• Gene: SSE1 / 855998
• SGDID: S000006027
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 707
• Identity: 186/707 - (26%)
• Similarity: 327/707 - (46%)
• Gaps: 103/707 - (14%)

  Fly     8 GIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAKR 72
            |:|||...|.:.|.:|..::|:.|:..||:|||.|.|....|.:|:..||:...|.||||.:.||
Yeast     6 GLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKR 70

  Fly    73 LIGRKFDDKKIQEDLKLWPFKVIN-EKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYLG 136
            :||..:.....:::.|.:..|::. :..|...||.|.||:..|:..::::|.:.|:::..:....
Yeast    71 IIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTK 135

  Fly   137 GKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN--LKGE---RNVL 196
            ..:.|..:.||.::.:.||....||..|||||.:||:|:.|||.::||:.|.  .:||   |.|.
Yeast   136 ANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVA 200

  Fly   197 IFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARAL 261
            ..|:|..::..|:::..:|.| :|..||.|.|.||.|||..:..|||:|||.|:|.||:.|.:|.
Yeast   201 FVDIGHSSYTCSIMAFKKGQL-KVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAY 264

  Fly   262 RRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAK 326
            .|:.||.|:.|:.||::|.|...::::...:|..|::||...|||...|.....:||.:||:.||
Yeast   265 NRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKALAQAK 329

  Fly   327 MDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQD 391
            :..:.:..|.::||:||||.:::.:.:.| ||.|:.::|.|||:|.|||...||.:  .:.:::.
Yeast   330 LSAEEVDFVEIIGGTTRIPTLKQSISEAF-GKPLSTTLNQDEAIAKGAAFICAIHS--PTLRVRP 391

  Fly   392 LLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSD--NQNAVTIQVYEGERAMTKDN 454
            ....|:.|.|:...     ....||..     ...::|...|.  :...:|:.       .|.|.
Yeast   392 FKFEDIHPYSVSYS-----WDKQVEDE-----DHMEVFPAGSSFPSTKLITLN-------RTGDF 439

  Fly   455 NLLGTF-NLTGIPP---------------APRGVPQIEVAFDLNAD--GILNVN----------- 490
            ::..:: ::|.:||               .|.|...:.|...|..|  |:..:.
Yeast   440 SMAASYTDITQLPPNTPEQIANWEITGVQLPEGQDSVPVKLKLRCDPSGLHTIEEAYTIEDIEVE 504

  Fly   491 -----------------AKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQ 538
                             .|...|.|.:.:||......|...:::.::.:..:...:|....|...
Yeast   505 EPIPLPEDAPEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETED 569

  Fly   539 SKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNS------------------ 585
            .||.||.|||..|..:::..:...|:.|::|::...:....||....
Yeast   570 RKNTLEEYIYTLRGKLEEEYAPFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYIAKYEELASL 634

  Fly   586 --------LAEKEEFESHLKECQRI--CTPIMSKIHGGKKGKSSMGKGSHPTVEEVD 632
                    ||::||.:..::..|..  ...:..|:...:|.::...:....|..:||
Yeast   635 GNIIRGRYLAKEEEKKQAIRSKQEASQMAAMAEKLAAQRKAEAEKKEEKKDTEGDVD 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	184/705 (26%)
SSE1	NP_015219.1	ASKHA_ATPase-like	4..644	CDD:483947	176/658 (27%)