Protein Alignment Hsc70-2 and SSB2

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_014190.1
• Gene: SSB2 / 855512
• SGDID: S000005153
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 609
• Identity: 354/609 - (58%)
• Similarity: 450/609 - (73%)
• Gaps: 12/609 - (1%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |||||||||||||..:::| ||||||:||||.|||:|||...||||||.||||.|:|.:||||||
Yeast     9 AIGIDLGTTYSCVATYESS-VEIIANEQGNRVTPSFVAFTPQERLIGDAAKNQAALNPRNTVFDA 72

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||:|||:.:|:|:|.||||||:..|.|.|||::..|.|.|:|:|||:||||||:||||..:
Yeast    73 KRLIGRRFDDESVQKDMKTWPFKVIDVDGNPVIEVQYLEETKTFSPQEISAMVLTKMKEIAEAKI 137

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGL--DKNLKGERNVLIF 198
            |.||:.||:||||||||:|||||||||:|:|||||||||||||||:||||  .|:.| ||:||||
Yeast   138 GKKVEKAVITVPAYFNDAQRQATKDAGAISGLNVLRIINEPTAAAIAYGLGAGKSEK-ERHVLIF 201

  Fly   199 DLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRR 263
            ||||||||||:|.| .|.::.||:|:|:|||||:|||..|:.||..|||:|...||..:||||||
Yeast   202 DLGGGTFDVSLLHI-AGGVYTVKSTSGNTHLGGQDFDTNLLEHFKAEFKKKTGLDISDDARALRR 265

  Fly   264 LRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMD 328
            ||||.|||||||||.|:.::|:|:|.:|.||.|.::|||||:||..||:||::|||:.|.|||:.
Yeast   266 LRTAAERAKRTLSSVTQTTVEVDSLFDGEDFESSLTRARFEDLNAALFKSTLEPVEQVLKDAKIS 330

  Fly   329 KKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSS-QIQDL 392
            |..|.:||||||||||||:||||.|.|.||||..|||||||||||||||.|||||..:| :.:||
Yeast   331 KSQIDEVVLVGGSTRIPKVQKLLSDFFDGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDL 395

  Fly   393 LLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLL 457
            ||:||||||||:...|.:...:|.||..:|..:::.|||.||||..|...||:|||...|:|.||
Yeast   396 LLLDVAPLSLGVGMQGDIFGIVVPRNTTVPTIKRRTFTTVSDNQTTVQFPVYQGERVNCKENTLL 460

  Fly   458 GTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSE 522
            |.|:|..||..|.|.|.:|..|:::|:|||.|.|.:.|||||..|||||..||||..||::|:::
Yeast   461 GEFDLKNIPMMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSSNITISNAVGRLSSEEIEKMVNQ 525

  Fly   523 AEKYKVEDDRQRERVQSKNNLEAYIYACRQAV-DDAPSGVLSETERSKVRDKCSS--EASWLDKN 584
            ||::|..|:...::.:::..||:|:.:..|.| |...|..|....:||:....|.  .|..::..
Yeast   526 AEEFKAADEAFAKKHEARQRLESYVASIEQTVTDPVLSSKLKRGSKSKIEAALSDALAALQIEDP 590

  Fly   585 SLAEKEEFESHLKECQRICTPIMS 608
            |..|..:.|..||   |:.|..||
Yeast   591 SADELRKAEVGLK---RVVTKAMS 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	354/609 (58%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	258/377 (68%)
SSB2	NP_014190.1	PTZ00009	6..575	CDD:240227	343/568 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.640