Protein Alignment Hsc70-2 and SSC1

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_012579.1
• Gene: SSC1 / 853503
• SGDID: S000003806
• Length: 654
• Species: Saccharomyces cerevisiae
• Alignment Length: 633
• Identity: 295/633 - (46%)
• Similarity: 420/633 - (66%)
• Gaps: 33/633 - (5%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF-NETERLIGDPAKNQVAMNAKNTVFDA 70
            ||||||||.|.|.:.:....:||.|.:|:|||||.||| .|.|||:|.|||.|..:|.:||:|..
Yeast    33 IGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFAT 97

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||:|:|.::|.|:|..|:|:: :.......||.:|:  .::|.:|...||.||:|.||.||
Yeast    98 KRLIGRRFEDAEVQRDIKQVPYKIV-KHSNGDAWVEARGQ--TYSPAQIGGFVLNKMKETAEAYL 159

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |..||:|||||||||||||||||||||.|.||||||::||||||||||||:|:  ..:.|.:|||
Yeast   160 GKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKS--DSKVVAVFDL 222

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||:|:|.||.| :||||:|.|||||||||||..|:......||.:...|::.:..|::|:|
Yeast   223 GGGTFDISILDIDNG-VFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIR 286

  Fly   266 TACERAKRTLSS--STEASLE-IDALHEGIDFYS-KISRARFEELNMDLFRSTMQPVERALSDAK 326
            .|.|:||..|||  |||.:|. |.|...|....: |.|||:||.|...|.:.|:.||::||.||.
Yeast   287 EAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAG 351

  Fly   327 MDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQD 391
            :....|.:|:||||.:|:||:.:.::.|| ||..:.::|||||||.|||||.|:|:|    ::.|
Yeast   352 LSTSDISEVLLVGGMSRMPKVVETVKSLF-GKDPSKAVNPDEAVAIGAAVQGAVLSG----EVTD 411

  Fly   392 LLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNL 456
            :||:||.||||||||.|||.|.|:.||..||.|:.|||:|.:..|.:|.|:|::|||.:.:||.|
Yeast   412 VLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKL 476

  Fly   457 LGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLS 521
            :|.|.|.||||||:|||||||.||::||||:||:|:|.:|.|...||::...| ||:.||::|::
Yeast   477 IGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSG-LSENEIEQMVN 540

  Fly   522 EAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPS------GVLSETERSKVRDKCSSEASW 580
            :|||:|.:|:.:::.:::.|..:       |..:|..:      |.:.:.|..||||:.:|....
Yeast   541 DAEKFKSQDEARKQAIETANKAD-------QLANDTENSLKEFEGKVDKAEAQKVRDQITSLKEL 598

  Fly   581 LDKNSLAEK---EEFESHLKECQRICTPIMSKIHGGKKGKSSMGKGSH 625
            :.:....|:   ||.::..:|.|.....:..:::......::...|::
Yeast   599 VARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNN 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	295/633 (47%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	199/379 (53%)
SSC1	NP_012579.1	dnaK	30..633	CDD:234715	294/618 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810