Protein Alignment Hsc70-2 and SSE2

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_009728.1
• Gene: SSE2 / 852467
• SGDID: S000000373
• Length: 693
• Species: Saccharomyces cerevisiae
• Alignment Length: 643
• Identity: 191/643 - (29%)
• Similarity: 329/643 - (51%)
• Gaps: 71/643 - (11%)

  Fly     8 GIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAKR 72
            |:|||...|.:.|.:|..::::.|:..||:|||.|.|....|.:|:..|.:...|.||||.:.||
Yeast     6 GLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKR 70

  Fly    73 LIGRKFDDKKIQEDLKLWPFKVINEK-GKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYLG 136
            :||.||.|.:...:.|.:..|::..| ||..:||||.|:...|:..::::|.:.|::...:....
Yeast    71 IIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETK 135

  Fly   137 GKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN-LKG----ERNVL 196
            ..:.|..:.||.::::.||....||..|||||.:||:|:.||||::||:.|| |.|    .|.:.
Yeast   136 SSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIG 200

  Fly   197 IFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARAL 261
            :.|:|..|:..|:::..:|.: :|..||.|.|.||.|||..:..|||::||.|:|.||:.|.:|.
Yeast   201 LVDIGHSTYTCSIMAFRKGEM-KVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAY 264

  Fly   262 RRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAK 326
            .|:..|.|:.|:.||::|.|...::::.:.||..|::||...|||...|.:....|:..||:.||
Yeast   265 NRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAK 329

  Fly   327 MDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQD 391
            :....|..|.::||:||||.::|.:.|:| ||.|:.::|.|||||.|||...||.:  .:.:::.
Yeast   330 LTVNDIDFVEIIGGTTRIPVLKKSISDVF-GKPLSSTLNQDEAVAKGAAFICAIHS--PTLRVRP 391

  Fly   392 LLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYE-GERAM----T 451
            ....|:.|.|:..     .....|:...|:     ::|...|...:...|.::. |:.:|    |
Yeast   392 FKFEDIDPYSVSY-----TWDKQVDDEDRL-----EVFPANSSYPSTKLITLHRTGDFSMKAVYT 446

  Fly   452 KDNNL-------LGTFNLTGIPPAPRGVPQIEVAFDLNAD--GI-------------------LN 488
            ..:.|       :..::.||: ..|:....|.|...|..|  |:                   |.
Yeast   447 HPSKLPKGTSTTIAKWSFTGV-KVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLP 510

  Fly   489 VNAKDNSTGKSEKITISNDKG---------RLSKAEIDRMLSEAEKYKVEDDRQRERVQSKNNLE 544
            .:|.:::..:.:::|.:..|.         .|:..|::.::.:..:.:.:|....|....||.||
Yeast   511 EDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALE 575

  Fly   545 AYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWL----DKNS----LAEKEEFES 594
            .|||..|..:||..|...|:.|:.|:::..::..:||    |.::    :|:.||..|
Yeast   576 EYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELAS 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	191/643 (30%)
SSE2	NP_009728.1	ASKHA_ATPase-like	5..390	CDD:483947	142/387 (37%)