Protein Alignment Hsc70-2 and SSA1

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_009396.2
• Gene: SSA1 / 851259
• SGDID: S000000004
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 642
• Identity: 432/642 - (67%)
• Similarity: 516/642 - (80%)
• Gaps: 18/642 - (2%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |:|||||||||||..:.|.:|:|||||||||||||:|||.:|||||||.||||.|||..||||||
Yeast     4 AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDA 68

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||.|:|.::|.|:|.:|||:|:..|||:|:||||||.|.|.||:||||||.||:|.||.||
Yeast    69 KRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYL 133

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |.||.||||||||||||||||||||||:|||||||||||||||||:||||||..| |.:||||||
Yeast   134 GAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGK-EEHVLIFDL 197

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|||::| :|||||||||||||||||||||||||.:|||||:|.|:..|.|||||||
Yeast   198 GGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLR 261

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            |||||||||||||.:.|:|||:|.||||||:.|:|||||||..||||||:.|||:.|.|||:||.
Yeast   262 TACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKS 326

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395
            .:.::|||||||||||:|||:.|.|.||:.|.|||||||||||||||||||||..||:.|||||:
Yeast   327 QVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLL 391

  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460
            |||||||||||||||||.|:.||:.||.|:.:||:||:|||..|.|||:|||||.||||||||.|
Yeast   392 DVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKF 456

  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525
            .|:||||||||||||||.||::::|||||:|.:..||||.||||:||||||||.:|::|::||||
Yeast   457 ELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEK 521

  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAEKE 590
            :|.||:::.:|:.|||.||:..|:.:..:.:| ...|.:.::..|..|.....||||.|:.|.||
Yeast   522 FKEEDEKESQRIASKNQLESIAYSLKNTISEA-GDKLEQADKDTVTKKAEETISWLDSNTTASKE 585

  Fly   591 EFESHLKECQRICTPIMSKIH--GGKKGKSSMG-------------KGSHPTVEEVD 632
            ||:..|||.|.|..|||||::  ||..|.::.|             :...|||||||
Yeast   586 EFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPGGAPPAPEAEGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	430/640 (67%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	284/375 (76%)
SSA1	NP_009396.2	PTZ00009	4..642	CDD:240227	430/640 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720