Protein Alignment Hsc70-2 and SSA2

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_013076.1
• Gene: SSA2 / 850636
• SGDID: S000003947
• Length: 639
• Species: Saccharomyces cerevisiae
• Alignment Length: 639
• Identity: 427/639 - (66%)
• Similarity: 514/639 - (80%)
• Gaps: 15/639 - (2%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |:|||||||||||..:.|.:|:|||||||||||||:|.|.:|||||||.||||.|||..||||||
Yeast     4 AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFTDTERLIGDAAKNQAAMNPANTVFDA 68

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||.|:|.::|.|:|.:|||:|:..|||:|:||||||.|.|.||:||||||.||:|.||.||
Yeast    69 KRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYL 133

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |.||.||||||||||||||||||||||:|||||||||||||||||:||||||..| |.:||||||
Yeast   134 GAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGK-EEHVLIFDL 197

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|||::| :|||||||||||||||||||||||||.:|||||:|.|:..|.|||||||
Yeast   198 GGGTFDVSLLSIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLR 261

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            |||||||||||||.:.|:|||:|.||||||:.|:|||||||..||||||:.|||:.|.|||:||.
Yeast   262 TACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKS 326

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395
            .:.::|||||||||||:|||:.|.|.||:.|.|||||||||||||||||||||..||:.|||||:
Yeast   327 QVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLL 391

  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460
            |||||||||||||||||.|:.||:.||.|:.::|:||:|||..|.|||:|||||.||||||||.|
Yeast   392 DVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKF 456

  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525
            .|:||||||||||||||.||::::|||||:|.:..||||.||||:||||||||.:|::|::||||
Yeast   457 ELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEK 521

  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAEKE 590
            :|.||:::.:|:.|||.||:..|:.:..:.:| ...|.:.::..|..|.....:|||.|:.|.||
Yeast   522 FKEEDEKESQRIASKNQLESIAYSLKNTISEA-GDKLEQADKDAVTKKAEETIAWLDSNTTATKE 585

  Fly   591 EFESHLKECQRICTPIMSKIH---GGKKGKSSMG---------KGSHPTVEEVD 632
            ||:..|||.|.:..|||||::   |..:|.:..|         :...|||||||
Yeast   586 EFDDQLKELQEVANPIMSKLYQAGGAPEGAAPGGFPGGAPPAPEAEGPTVEEVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	425/637 (67%)
SSA2	NP_013076.1	PTZ00009	4..639	CDD:240227	425/637 (67%)