DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsc70-2 and AT3G09440

DIOPT Version :9

Sequence 1:	NP_524339.1	Gene:	Hsc70-2 / 41609	FlyBaseID:	FBgn0001217	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_001189847.1	Gene:	AT3G09440 / 820102	AraportID:	AT3G09440	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	648	Identity:	435/648 - (67%)
Similarity:	522/648 - (80%)	Gaps:	20/648 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNT 66
            |:.||||||||||||||||||:.:|||||||||||||||||||.::||||||.||||||||..||
plant     5 GEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPINT 69

  Fly    67 VFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKG---KPKIEVEFKGERKRFAPEEISSMVLTKMR 128
            ||||||||||:|.|..:|.|:|||||.:  :.|   ||.|.|.:|||.|.|:.||||||:|.|||
plant    70 VFDAKRLIGRRFTDSSVQSDIKLWPFTL--KSGPAEKPMIVVNYKGEDKEFSAEEISSMILIKMR 132

  Fly   129 EIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLK--G 191
            ||||.|||..:|:|||||||||||||||||||||.||||||:||||||||||:||||||...  |
plant   133 EIAEAYLGTTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVG 197

  Fly   192 ERNVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKG 256
            |:|||||||||||||||:|:|:|| :||||||||||||||||||||:||||.:|||||:|.||.|
plant   198 EKNVLIFDLGGGTFDVSLLTIEEG-IFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISG 261

  Fly   257 NARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERA 321
            |.|||||||||||||||||||:.:.::|||:|.:|||||:.|:||||||||:||||..|:|||:.
plant   262 NPRALRRLRTACERAKRTLSSTAQTTIEIDSLFDGIDFYAPITRARFEELNIDLFRKCMEPVEKC 326

  Fly   322 LSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGS 386
            |.||||||.:|.|||||||||||||:|:||.|.|.||:|..|||||||||||||||||||:|.|:
plant   327 LRDAKMDKNSIDDVVLVGGSTRIPKVQQLLVDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGN 391

  Fly   387 SQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMT 451
            .::|||||:||.|||||:||||||||.|::||..||.|::|:|:||||||..|.|||||||||.|
plant   392 EKVQDLLLLDVTPLSLGLETAGGVMTVLIQRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERART 456

  Fly   452 KDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEI 516
            |||||||.|.|:||||||||||||.|.||::|:|||||:|:|.:||:..||||:||||||||.||
plant   457 KDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEI 521

  Fly   517 DRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSG-VLSETERSKVRDKCSSEASW 580
            ::|:.||||||.||:..:::|.:||.||.|.|..|..:.|...| .|:..::.|:.|...:...|
plant   522 EKMVQEAEKYKSEDEEHKKKVDAKNALENYAYNMRNTIRDEKIGEKLAGDDKKKIEDSIEAAIEW 586

  Fly   581 LDKNSLAEKEEFESHLKECQRICTPIMSKIH-GGKKGKSSMG----------KGSHPTVEEVD 632
            |:.|.|||.:|||..:||.:.||.||::|:: ||:.|..:.|          .|:.|.:||||
plant   587 LEANQLAECDEFEDKMKELESICNPIIAKMYQGGEAGGPAAGGMDEDVPPSAGGAGPKIEEVD 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	433/646 (67%)
Hsc70-2	NP_524339.1	HSPA1-2_6-8-like_NBD	6..382	CDD:212675	289/380 (76%)
AT3G09440	NP_001189847.1	PTZ00009	5..649	CDD:240227	433/646 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730