Protein Alignment Hsc70-2 and hspa1b

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001093532.1
• Gene: hspa1b / 798846
• ZFINID: ZDB-GENE-060503-867
• Length: 639
• Species: Danio rerio
• Alignment Length: 644
• Identity: 462/644 - (71%)
• Similarity: 537/644 - (83%)
• Gaps: 17/644 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|..:||||||||||||||:|:.||||||||||||||||||||.:|||||||.||||||||..|
Zfish     1 MAKGLSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |:|||||||||||||:.:|.|:||||||||:|.||||::||:|||.|.|.|||||||||.|||||
Zfish    66 TIFDAKRLIGRKFDDQVVQSDMKLWPFKVISEDGKPKVQVEYKGENKTFYPEEISSMVLVKMREI 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            ||.|||.:|.:||:||||||||||||||||||.|||||||||||||||||:||||||..||||||
Zfish   131 AEAYLGHRVNNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGRKGERNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|:|::| :||||||||||||||||||||:|.||.||||||||.||..|.||
Zfish   196 LIFDLGGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVKHFVEEFKRKHKKDISQNKRA 259

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            :|||||||||||||||||::||:|||:|.||||||:.|:||||||||.:|||.|:.|||:||.||
Zfish   260 VRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEELNAELFRGTLDPVEKALRDA 324

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            ||||..|.|:||||||||||||||||||.|.|:.||.|||||||||||||||||||.|..|..:|
Zfish   325 KMDKSQIQDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDTSENVQ 389

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            ||||:|||||||||||||||||.|::||..||.||.|||:||||||..|.|||:|||||||||||
Zfish   390 DLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFSTYSDNQPGVLIQVFEGERAMTKDNN 454

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            |||.|:||||||||||||||||.||::|:|||||:|.|.||||..||||:||||||||.:|:||:
Zfish   455 LLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKENKITITNDKGRLSKEDIERMV 519

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKN 584
            .:|||||.||:.|||::.:||.||:|.::.:..|:|.. .|.:||.::.|:.|||:...|||:.|
Zfish   520 QDAEKYKAEDEVQREKIAAKNALESYAFSMKNTVEDENLRGKISEQDKKKIIDKCTEVVSWLENN 584

  Fly   585 SLAEKEEFESHLKECQRICTPIMSKIHGG-----------KKGKSSMGKGSHPTVEEVD 632
            .||||||:|.|.||.:.:|.||:|:::.|           .:.:||.|    ||:||||
Zfish   585 QLAEKEEYEHHQKELESVCNPIISRLYQGGAPPAGGCGFQAQPESSQG----PTIEEVD 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	460/642 (72%)
hspa1b	NP_001093532.1	PTZ00009	1..639	CDD:240227	460/642 (72%)