Protein Alignment Hsc70-2 and hspa12a

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001417784.2
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 670
• Species: Danio rerio
• Alignment Length: 657
• Identity: 141/657 - (21%)
• Similarity: 236/657 - (35%)
• Gaps: 200/657 - (30%)

  Fly     4 IPAIGIDLGTTYS-----------CVGV---WQNSKVEIIANDQG--NRTTPSYVAFNETERLIG 52
            :..:.||.|||.|           |:..   |:       ..|.|  |:.||:      |..|..
Zfish    53 VVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWE-------GGDPGVSNQKTPT------TILLTP 104

  Fly    53 DPAKNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKV-INEKGKPKIEVEFKGER-KRFA 115
            |...:.....|::...|        .|..:.::.|.|..||: ::......|:.:..... |:..
Zfish   105 DKKFHSFGYAARDFYHD--------LDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVK 161

  Fly   116 PEEISSMVLTKMREIAEVYL----GGKVKDA----VVTVPAYFNDSQRQATKDAGSIAGL----- 167
            ..:|.:..|...:|.|...|    |.:..:|    |:||||.:....:|..::|...|.|
Zfish   162 ALDIFAYALAFFKEQALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTREN 226

  Fly   168 -NVLRIINEPTAAAL--------------------AYGLDKN----------------------- 188
             :.|.|..||.||::                    .|....|
Zfish   227 PDQLIIALEPEAASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLV 291

  Fly   189 -----------LKGERNVLIFDLGGGTFDVSV--LSIDEGSLFEV-KATAGDTHLGGED--FDNR 237
                       .:|:|.|:: |.||||.|::|  :.:.||.|.|: ||:.|.....|.|  |:..
Zfish   292 ENVIGELWSELAEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEKL 355

  Fly   238 LVNHFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRAR 302
            |...|.::|..:.|  ||..| |...|..|.|..||..:......|.|:.....||:|.|.....
Zfish   356 LCKIFGQDFIDQFK--IKRPA-AWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGHS 417

  Fly   303 FE----ELNMD-------------------LFRSTMQPVERALSDAKMDKKAIHDV---VLVGGS 341
            .|    :.|:|                   ||:.|:..:.:.|::. .|:..:.|:   .||||.
Zfish   418 VEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGGF 481

  Fly   342 TRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLVDVAPLSLGIET 406
            ...|.:|:.:|::..|:. .:.|..|..:   ..::.|:|.|:..|    ::.|..:||:.|:
Zfish   482 AESPLLQQAVQNMLQGRS-RIIIPHDVGL---TILKGAVLFGLDPS----IIKVRRSPLTYGV-- 536

  Fly   407 AGGVMTNLVERNARIPCKQQ----------QIFTTY--------------------SDNQNAVTI 441
              ||:...||  .:.|.::.          .:|.|:                    ..:|..:.|
Zfish   537 --GVLNRFVE--GKHPPEKMLVKDGMRWCTDVFDTFISADQSVALGETVKRSYTPAKPSQQVIVI 597

  Fly   442 QVYEGER---------AMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTG 497
            .||..|:         .:.|..:|....:.|..|.|.|.: |..:.|   .|..:...|.|.:|.
Zfish   598 HVYCSEKESVTFITDPGVRKCGSLKLDVSGTESPAARREI-QTLMQF---GDTEIRAMAVDVATS 658

  Fly   498 KSEKITI 504
            ::.|.:|
Zfish   659 RTVKASI 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	141/657 (21%)
hspa12a	NP_001417784.2	None