DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsc70-2 and Ankrd45

DIOPT Version :9

Sequence 1:	NP_524339.1	Gene:	Hsc70-2 / 41609	FlyBaseID:	FBgn0001217	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	XP_030099044.2	Gene:	Ankrd45 / 73844	MGIID:	1921094	Length:	313	Species:	Mus musculus

Alignment Length:	147	Identity:	27/147 - (18%)
Similarity:	60/147 - (40%)	Gaps:	29/147 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   475 IEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQS 539
            :|:..|:.|.......|:|.:             .|.|:.|....|..|:...:     .:::.:
Mouse   190 VELDVDIEALNFRGEKARDVA-------------ARYSQVECVNFLDWADARLI-----LKKIIT 236

  Fly   540 KNNLEAYIYACRQAVDDAPS--GVLSETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQRI 602
            |::|         .:.|...  |.|.:.::|.:.:.|..:..||:.:..|...|.....::.:.|
Mouse   237 KSSL---------IITDPEKGPGKLFKEDKSTILNACRLKNEWLESHPEASISEIFEQKQQLEDI 292

  Fly   603 CTPIMSKIHGGKKGKSS 619
            .:||::|:...::.||:
Mouse   293 VSPILAKMSTPRQVKSA 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	27/147 (18%)
Hsc70-2	NP_524339.1	HSPA1-2_6-8-like_NBD	6..382	CDD:212675
Ankrd45	XP_030099044.2	Ank_2	123..200	CDD:403870	3/9 (33%)
		ANK repeat	137..167	CDD:293786
		ANK repeat	169..200	CDD:293786	3/9 (33%)
		PTZ00009	<246..300	CDD:240227	11/53 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900