Protein Alignment Hsc70-2 and hspa12b

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001036151.1
• Gene: hspa12b / 735291
• ZFINID: ZDB-GENE-070226-1
• Length: 691
• Species: Danio rerio
• Alignment Length: 674
• Identity: 138/674 - (20%)
• Similarity: 234/674 - (34%)
• Gaps: 212/674 - (31%)

  Fly     7 IGIDLGTT---YSCVGVWQNSKVEIIANDQG------NRTTPSYVAFNETERLIGDPAKNQVAMN 62
            :.||.|||   |:...:.....:.::...:|      |:.:|:.:.      |..|...:.....
Zfish    63 VAIDFGTTSSGYAFSFIEDPETIHMMRRWEGGDPGVANQKSPTCLL------LTPDLRFHSFGFA 121

  Fly    63 AKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKV-INEKGKPKIEVEFKG-ERKRFAPEEISSMVLT 125
            |:::..|        .|.::.:..|....||: |:......:|.|.:. ..:|....|:.:..|.
Zfish   122 ARDSYHD--------LDPEEARHWLYFDKFKMKIHSTSDLTMETELESVSGRRVQAIEVFAHALR 178

  Fly   126 KMREIA---------EVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGL------NVLRIINE 175
            ..||.|         .|..|.:|: .|:||||.:....:|..::|..:|||      ..|.|..|
Zfish   179 FFREHALKEVKDQSSSVLEGNEVR-WVITVPAVWRQPAKQFMREAAYLAGLVPPDSPEQLLIALE 242

  Fly   176 PTAAAL------------------AYGLDKNLKGER----------------------------- 193
            |.||::                  ..|.|  :.|.|
Zfish   243 PEAASIYCRKLRLHQVTDLSQRPVTNGFD--IDGSRPFDSSFRQAREQLRRARHSRTFLVESGTG 305

  Fly   194 ----------NVLIFDLGGGTFDVSVLSID--EGSLFEV-KATAGDTHLGGED--FDNRLV---- 239
                      ..::.|.||||.|::|..|:  :|:|.|: ||:.|.....|.|  |:..|.
Zfish   306 ELWSEMQTGDRYIVADCGGGTVDLTVHQIEQPQGTLKELYKASGGPYGAVGVDLAFETMLCQIFG 370

  Fly   240 NHFAEEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYS-------- 296
            ..|.:.||.|..:       |...|..|.|..|||.:.....:|.|......||||.
Zfish   371 TDFIDSFKAKRPA-------AWVDLTIAFEARKRTAAPGRANTLNISLPFSFIDFYKQHRGQSVE 428

  Fly   297 ---KISRARF------------EELNMDLFRSTMQPVERALSDA--KMDKKAIHDVVLVGGSTRI 344
               :.|...|            .|...:||:.|:..:.:.:.:.  |.:.|.:..:.||||....
Zfish   429 TALRKSNMNFIKWSSQGMLRLSTEATNELFQPTINNIIKHIENVMQKEEVKGVRFLFLVGGFAES 493

  Fly   345 PKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLVDVAPLSLGIETAGG 409
            |.:|:.:|:.. |:...:.|..|..:   ..::.|:|.|:..:.::    |...||:.|:    |
Zfish   494 PMLQRAIQNTL-GRNCRIIIPHDVGL---TILKGAVLFGLDPTVVR----VRRCPLTYGV----G 546

  Fly   410 VMTNLVE----------RNARIPCKQ------------------QQIFTTYSDNQNAVTIQVYEG 446
            |:...||          ::.|..|..                  ::.:|.....|..:.|.:|..
Zfish   547 VLNRFVEGRHPHDKLLIKDGREWCTDILDRFVSVDQSVALGEVVRRSYTPARMGQRKIIINIYCS 611

  Fly   447 ERAMTKDNNLLGTFNLTGIPPAPRGVPQI-EVAFDLNADGILNVNAKDNSTGKS----------- 499
            :           |.::|.|  ...||.:. .:..||...|..:.:..||..|.:
Zfish   612 D-----------TDDITYI--TDPGVRKCGAITLDLLESGEASASTGDNDKGSAFERREIRTTMQ 663

  Fly   500 -----EKIT-ISNDKGRLSKAEID 517
                 .|:| :....|||.:|.||
Zfish   664 FGDTEIKVTAVDVATGRLVRASID 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	138/674 (20%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	103/491 (21%)
hspa12b	NP_001036151.1	HSPA12B_like_NBD	61..529	CDD:212686	104/493 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910