Protein Alignment Hsc70-2 and Hspa12b

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_082582.1
• Gene: Hspa12b / 72630
• MGIID: 1919880
• Length: 685
• Species: Mus musculus
• Alignment Length: 657
• Identity: 148/657 - (22%)
• Similarity: 233/657 - (35%)
• Gaps: 198/657 - (30%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEII-------ANDQG--NRTTPS---------YVAFNETERLIGD 53
            :.||.|||.|.......|..|.|       ..|.|  ::.||:         :.:|..|.|   |
Mouse    63 VAIDFGTTSSGYAFSFASDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPEGIFHSFGYTAR---D 124

  Fly    54 PAKNQVAMNAKNTVFDAKRLIGRKFDDKKIQ----EDLKL-WPFKVINEKGKPKIEVEFKGERKR 113
            ...:.....|::.::         |:..|::    .||.| ...:.:|  ||..:.:|......|
Mouse   125 YYHDLDPEEARDWLY---------FEKFKMKIHSATDLTLKTQLEAVN--GKKMLALEVFAHALR 178

  Fly   114 FAPEEISSMVLTKMREIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGL------NVLRI 172
            |..|.    .|.::||.:|..|.......|:||||.:....:|..::|..:|||      ..|.|
Mouse   179 FFKEH----ALQELREQSECMLEKGAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLI 239

  Fly   173 INEPTAAAL-------------------------AYGLDKNLKGERNVL---------------- 196
            ..||.||::                         ...:|.:.:..|..|
Mouse   240 ALEPEAASVYCRKLRLHQLMDLSSRTAGRGRLGERRSIDSSFRHAREQLRRSRHSRTFLVEAGVG 304

  Fly   197 -------------IFDLGGGTFDVSVLSIDE--GSLFEV-KATAGDTHLGGED--FDNRLVNHFA 243
                         :.|.||||.|::|..:::  |:|.|: ||:.|.....|.|  |:..|...|.
Mouse   305 ELWAEMQEGDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFG 369

  Fly   244 EEFKRKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSK----------- 297
            |:|..|.|   :....|...|..|.|..|||.......:|.|......||||.|
Mouse   370 EDFIAKFK---RQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALR 431

  Fly   298 -------------ISRARFEELNMDLFRST----MQPVERALSDAKMDKKAIHDVVLVGGSTRIP 345
                         :.|...|.:| :||:.|    :|.:|..|  ||.:.:.:..:.||||.....
Mouse   432 RSSVNLVKWSSQGMLRMSCEAMN-ELFQPTVSGIIQHIEMLL--AKPEVQGVKLLFLVGGFAESA 493

  Fly   346 KIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLVDVAPLSLGIETAGGV 410
            .:|..:|:..|.:.|.:.:..|..:   ..::.|:|.|    |...::.|..:||:.|:    ||
Mouse   494 VLQHAVQEALGTRGLRVVVPHDVGL---TILKGAVLFG----QAPGVVRVRRSPLTYGV----GV 547

  Fly   411 MT----------NLVERNARIPCKQ---------------QQIFTTY---SDNQNAVTIQVY--- 444
            :.          .|:.|:.|..|..               :::..:|   ...|..|.|.:|
Mouse   548 LNRFVPGHHPPEKLLVRDGRRWCTDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCA 612

  Fly   445 -EGERAMTKDN-NLLGTFNL----------TGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTG 497
             |..|.:|... ...|..:|          ||..|:.|   :|..|... .|..:.|.|.|.||.
Mouse   613 AEDARFITDPGVRKCGALSLELEPEGCPENTGTSPSRR---EIRAAMQF-GDTEIKVTAVDVSTN 673

  Fly   498 KSEKITI 504
            :|.:..|
Mouse   674 RSVRAAI 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	148/657 (23%)
Hspa12b	NP_082582.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50
		ASKHA_ATPase-like	61..528	CDD:483947	112/491 (23%)