Protein Alignment Hsc70-2 and HSPA13

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 160/434 - (36%)
• Similarity: 245/434 - (56%)
• Gaps: 57/434 - (13%)

  Fly     7 IGIDLGTTYSCVGVW--QNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFD 69
            |||||||||..|||:  ...||::|.::.|:.:.||.|:|.:.:..:|..:......|.:||::|
Human    34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYD 98

  Fly    70 AKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEF---KGERKRFAPEEISSMVLTKMREIA 131
            |||.||:.|..::::.::..:||||:|:.|.    |||   ..|....:||.:.|.:|.|::|:|
Human    99 AKRFIGKIFTAEELEAEIGRYPFKVLNKNGM----VEFSVTSNETITVSPEYVGSRLLLKLKEMA 159

  Fly   132 EVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVL 196
            |.|||..|.:||::|||.|:..||.:|.:|.::|||.:||:||||||||:||||.|  ....:||
Human   160 EAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHK--ADVFHVL 222

  Fly   197 IFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARAL 261
            :.||||||.|||:|: .:|.:|..:|.:|:..|||:||:.||:.:..::..:.: ..:......:
Human   223 VIDLGGGTLDVSLLN-KQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTY-GFVPSRKEEI 285

  Fly   262 RRLRTACERAKRTLSSSTEASLEI---------------------DALHEGID------------ 293
            .|||.|.|..|..|:....|.|.:                     |.|....|
Human   286 HRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLS 350

  Fly   294 ----------FYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKKAIHDVVLVGGSTRIPKIQ 348
                      |.::|||..|:.||.|||:..:.|:::.|.:..::|..|.:|||||||||||:|:
Human   351 DKKSGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIR 415

  Fly   349 KLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDL 392
            :::|:.| ||..|.|::||.||..|.|:||.|..|....|:..|
Human   416 QVIQEFF-GKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSAL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	160/434 (37%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	157/422 (37%)
HSPA13	NP_008879.3	HSPA13-like_NBD	12..463	CDD:212679	160/434 (37%)
		PRK13930	32..442	CDD:237564	153/416 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		3/36 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820