Protein Alignment Hsc70-2 and hspa8b

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 648
• Identity: 453/648 - (69%)
• Similarity: 530/648 - (81%)
• Gaps: 17/648 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|.||:|||||||||||||:|:.||||||||||||||||||||.:|||||||.||||||:|..|
Zfish     1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPTN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |||||||||||:|||..:|.|:|.|||.|||:..:||::||:|||.|.|.|||:||||||||:||
Zfish    66 TVFDAKRLIGRRFDDAVVQSDMKHWPFTVINDNLRPKVQVEYKGETKTFYPEEVSSMVLTKMKEI 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            ||.|||..:.:||:||||||||||||||||||:|:|||||||||||||||:||||||.:..||||
Zfish   131 AEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|:|::| :||||:|||||||||||||||:|.||..|||||:|.||..|.||
Zfish   196 LIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDISDNKRA 259

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            :||||||||||||||||||:||:|||:|:||||||:.|:||||||||.||||.|:.|||::|.||
Zfish   260 VRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKSLRDA 324

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            |:||..:||:||||||||||||||||||.|.||:||.|||||||||||||||||||.|..|..:|
Zfish   325 KLDKSQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQ 389

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            ||||:||.||||||||||||||.|::||..||.||.|.||||.|||..|.|||||||||||||||
Zfish   390 DLLLLDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVLIQVYEGERAMTKDNN 454

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            |||.|.||||||||||||||||.||::|:||:||:|.|.||||..||||:||||||||.:|:||:
Zfish   455 LLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMV 519

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKN 584
            .||||||.|||.|||:|.:||.||:|.:..:..|:|.. .|.:||.::.|:.:||:...||||||
Zfish   520 QEAEKYKAEDDVQREKVSAKNGLESYSFNMKSTVEDEKLKGKISEEDKQKIINKCNEVISWLDKN 584

  Fly   585 SLAEKEEFESHLKECQRICTPIMSKIH------------GGKKGKSSM---GKGSHPTVEEVD 632
            ..|||||||...||.:::|.||::|::            ||..|....   |..|.||:||||
Zfish   585 QTAEKEEFEHQQKELEKLCNPIITKLYQGTGGMPEGMPGGGFPGAGGAPGGGGSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	451/646 (70%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	442/612 (72%)