Protein Alignment Hsc70-2 and hspa4l

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_690505.2
• Gene: hspa4l / 562019
• ZFINID: ZDB-GENE-030131-2412
• Length: 826
• Species: Danio rerio
• Alignment Length: 723
• Identity: 203/723 - (28%)
• Similarity: 356/723 - (49%)
• Gaps: 114/723 - (15%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAK 71
            :|||:|.....:.|.::..:|.|||:..:|.||:.::.....|.||:.||:|:..|.||||...|
Zfish     4 VGIDVGFQNCYIAVARSGGIETIANEYSDRCTPACISLASKNRTIGNAAKSQIITNFKNTVHGFK 68

  Fly    72 RLIGRKFDDKKIQEDLKLWPFKVIN-EKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            :..||.|||..:|.:....|:.:.. :.|...|:|.:..|.|.|..|::::|:|||::|.:|..|
Zfish    69 KFHGRAFDDPFVQGEKSRLPYSLHKLDNGNAGIKVRYLNEDKVFTIEQVTAMLLTKLKETSEHAL 133

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN-----LKGERNV 195
            ...|.|.|::||::|.|.:|::..||..|||||.||:||:.||.|||||:.|.     .:..|||
Zfish   134 KKPVVDCVISVPSFFTDVERRSVMDATQIAGLNCLRLINDTTAVALAYGIYKQDLPNPEEKPRNV 198

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            :..|:|..::.|::.|.::|.| ::.|||.|.:|||.:||..||.:|.|:||.:.|.::|.|.||
Zfish   199 VFVDIGHSSYQVAIASFNKGKL-KMLATAFDPYLGGRNFDEILVEYFCEDFKNRFKLNVKDNPRA 262

  Fly   261 LRRLRTACERAKRTLS-SSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSD 324
            |.||...||:.|:.:| :|::..|.|:.....||.:.|::|.:|||:...|......|:...:..
Zfish   263 LLRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVHGKLNRTQFEEMCSQLMMRVEAPLRSVMEQ 327

  Fly   325 AKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQI 389
            :|:.:..|:.:.:|||:||:|.|::.:...| ||..:.::|.|||||.|:|:|.|||:  .:.::
Zfish   328 SKLSRDEIYAIEVVGGATRMPAIKERISKFF-GKDTSTTLNADEAVARGSALQCAILS--PAFKV 389

  Fly   390 QDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNA-----VTI---QVYEG 446
            ::..:.|..|..:.:........::.|      |:      .||.|..|     :|.   :.::.
Zfish   390 REFSITDTVPFPITLRWKSPTDESVGE------CE------VYSKNHPAPFSKIITFHKKEPFDL 442

  Fly   447 ERAMTKDNNL------LGTFNLTGIPPAPRG-VPQIEVAFDLNADGILNVNAK---DNSTGKSEK 501
            |...:..::|      :|.|::..:.|.|.| ..:::|...:|..||.:|::.   :...|:.|.
Zfish   443 EAFYSCPHDLPYPDVRIGRFSVQNVVPQPDGDSSKVKVKVRVNVHGIFSVSSASLIEKQKGEPED 507

  Fly   502 I------TISNDKGR---LSKAEIDR-----MLSEAE---------------------------- 524
            :      |:.|: ||   .||.::|:     ..||.|
Zfish   508 VQMDTEPTVQNE-GRPEEQSKMQVDQEGQGEQPSEEERANNSGIKDGDKQDQGASSSKAKSKVKS 571

  Fly   525 --------------------------KYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLS 563
                                      |..::|..::||..:||.:|.|:|..|..:.......::
Zfish   572 VDLPILANTTRQLDRDVLTHFVEYEKKMIIQDKLEKERNDAKNGVEEYVYDLRDKLCGIYEKYVT 636

  Fly   564 ETERSKVRDKCSSEASWL-DKNSLAEKEEFESHLKECQRICTPIMSKI--HGGK-KGKSSMGKGS 624
            |.|.:::........:|| ::....:||.::..|.|.::...||..:.  |.|: :....:||..
Zfish   637 EDESNRLTIMLEDTENWLYEEGEDQDKEIYQHKLAELKKYGEPIEERYREHEGRPRAFDELGKKL 701

  Fly   625 HPTVEEVD 632
            ...::.||
Zfish   702 QLFMKVVD 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	201/721 (28%)
hspa4l	XP_690505.2	ASKHA_ATPase-like	2..384	CDD:483947	143/381 (38%)