Protein Alignment Hsc70-2 and hspa12a.3

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 599
• Identity: 127/599 - (21%)
• Similarity: 242/599 - (40%)
• Gaps: 141/599 - (23%)

  Fly     7 IGIDLGTTYSCVGVWQNSK-----VEI----IANDQGNRTTPSYVAFNETE--RLIGDPA----- 55
            |.||.||:||...:...:|     ::|    :........||:.:.|:|.|  :..|..|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESIQIPNWGVNFGYNTFKTPTCILFDEHETFQKFGYDAMMTYT 72

  Fly    56 ----KNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAP 116
                |:|.   .|:.:|:..::   :..||:|..||.:    .....|:.|....| .|..|:
Zfish    73 RSTPKSQA---RKSFLFEHFKM---ELYDKEIHRDLMI----TAKNGGQMKALTVF-SESLRY-- 124

  Fly   117 EEISSMVLTKMRE--IAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNV------LRII 173
              :....|.|::|  ..:.::...| ..|:||||.:|.:.:|..::|...|||.:      |...
Zfish   125 --LKDHALEKIKENTTGKTFIASDV-TWVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFA 186

  Fly   174 NEPTAAALAYGLDKNLKGERNV-----------------LIFDLGGGTFDVSVLS-IDEGSLFEV 220
            .||.||::   ..|.|..|..:                 ::.|.||||.|::|.. :::|.|.|:
Zfish   187 LEPEAASI---YCKQLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKEL 248

  Fly   221 KATAGDTHLGGEDFDNRLVNH----FAEEFKRKHKSDIKGNARALR---RLRTACE-----RAKR 273
            .|.:|: .:||:..|.:.::.    |:|:...|.:.|....|..|:   .|..:|:     :...
Zfish   249 NAASGN-DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCPV 312

  Fly   274 TLSSSTEASLEIDALHEGIDFYSKISRARFEELNM------------DLFRSTMQPVERALSDAK 326
            ||....:....|::..||::      .|.::|.::            :..::|.:.:|:.:|:.:
Zfish   313 TLQDLAKKEKAIESYFEGVE------GAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPE 371

  Fly   327 MDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQD 391
            ::   |..::||||......::|.|::.|...::...:.|...:..| |::.|....|..|::..
Zfish   372 LN---IEYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKG-AIRYAKQPKVVKSRMSA 432

  Fly   392 L---LLVDVAPL-------------SLGIETAGGVMTNLVERNARIPCKQ-QQIFTTYSD-NQNA 438
            |   :.:| ||.             |.|...........|.:...:.|.: :|.|...|| ||..
Zfish   433 LTYGIRID-APFDKVLHKGKTSYVNSEGQTYCDVCFETFVRKGESVNCDEVRQFFFNPSDTNQTF 496

  Fly   439 VTIQVYEGERAMTKDNNL----------LGTFNLTGIPPAPRGVP---QIEVAFDLNADGILNVN 490
            .|.|.:.     |.:..:          :|.|.: |:|....|:.   ::|:.|....   :...
Zfish   497 ATFQFFS-----TNEKQVQFIDEPGVESVGVFQV-GMPKTDGGLSREIKLEIKFGSTE---MKAT 552

  Fly   491 AKDNSTGKSEKITI 504
            |.|..:|::..:.:
Zfish   553 ATDVDSGETTSVKL 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	127/599 (21%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	98/444 (22%)
hspa12a.3	NP_001038346.3	HSPA12_like_NBD	6..420	CDD:212671	97/441 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810