Protein Alignment Hsc70-2 and Hsp70Ab

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 478/642 - (74%)
• Similarity: 553/642 - (86%)
• Gaps: 13/642 - (2%)

  Fly     4 IPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVF 68
            :||||||||||||||||:|:.||||||||||||||||||||.::|||||||||||||||.:||||
  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65

  Fly    69 DAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEV 133
            |||||||||:||.||.||:|.|||||:::.|||||.||:|||.||||||||||||||||:|.||.
  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130

  Fly   134 YLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 198
            |||..:.|||:||||||||||||||||||.|||||||||||||||||||||||||||||||||||
  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195

  Fly   199 DLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRR 263
            ||||||||||:|:|||||||||::|||||||||||||||||.|.|:|||||:|.|::.|.|||||
  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRR 260

  Fly   264 LRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMD 328
            ||||.|||||||||||||::|||||.||.|||:|:||||||||..||||:|:||||:||:|||||
  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325

  Fly   329 KKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLL 393
            |..|||:|||||||||||:|.||||.|.||.||||||||||||||||||||||:|..|.:|||:|
  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390

  Fly   394 LVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLG 458
            |||||||||||||||||||.|:|||.||||||.:.|:||:|||..|:|||||||||||||||.||
  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALG 455

  Fly   459 TFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEA 523
            ||:|:||||||||||||||.|||:|:|||||:||:.||||::.|||.|||||||:||||||::||
  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520

  Fly   524 EKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAE 588
            |||..||::.|:|:.|:|.||:|::..:|||:.||:|.|.|.:::.|.|||:....|||.|:.||
  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585

  Fly   589 KEEFESHLKECQRICTPIMSKIH-----------GGKKGKSSMGKG--SHPTVEEVD 632
            ||||:..|:|..|.|:|||:|:|           |...|:.:.|.|  |.|||||||
  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	476/640 (74%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	312/375 (83%)
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	476/639 (74%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	312/375 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	1	1.000	-	-		H74294
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.750