Protein Alignment Hsc70-2 and hspa9

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001001229.1
• Gene: hspa9 / 407910
• XenbaseID: XB-GENE-960228
• Length: 670
• Species: Xenopus tropicalis
• Alignment Length: 616
• Identity: 293/616 - (47%)
• Similarity: 406/616 - (65%)
• Gaps: 65/616 - (10%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF-NETERLIGDPAKNQVAMNAKNTVFDA 70
            ||||||||.|||.:.:..:.:::.|.:|.|||||.||| ::.|||:|.|||.|...|..||.:..
 Frog    50 IGIDLGTTNSCVAIMEGKQAKVLENSEGARTTPSVVAFSSDAERLVGMPAKRQAVTNPNNTFYAT 114

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVIN-EKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVY 134
            ||||||:|||.::|:|:|..|||::. ..|...:|    ...|.::|.:|.:.||.||:|.||.|
 Frog   115 KRLIGRRFDDPEVQKDIKNVPFKIVKASNGDAWLE----SHGKLYSPSQIGAFVLMKMKETAENY 175

  Fly   135 LGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 199
            ||...|:||:||||||||||||||||||.|:||||||:|||||||||||||||:  .::.:.::|
 Frog   176 LGHAAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKS--DDKIIAVYD 238

  Fly   200 LGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRL 264
            |||||||:|:|.|.:| :||||:|.|||.|||||||..|:.|..::|||:...|:..:..||:|:
 Frog   239 LGGGTFDISILEIQKG-VFEVKSTNGDTFLGGEDFDQALLQHIVKQFKRESGVDLTKDNMALQRV 302

  Fly   265 RTACERAKRTLSSSTEASLEIDAL--------HEGIDFYSKISRARFEELNMDLFRSTMQPVERA 321
            |.|.|:||..|||:.:..:.:..|        |..:    |::||:||.:..||.:.|:.|.::|
 Frog   303 REAAEKAKCELSSALQTDINLPYLTMDASGPKHLNM----KLTRAQFEGIVADLIKRTVAPSQKA 363

  Fly   322 LSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGS 386
            :.||::.|..|.:|:||||.||:||:|:.:|||| |:..:.::|||||||.|||:|..:|.|
 Frog   364 MQDAEVGKSDIGEVLLVGGMTRMPKVQQTVQDLF-GRAPSKAVNPDEAVAIGAAIQGGVLAG--- 424

  Fly   387 SQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMT 451
             .:.|:||:||.||||||||.|||.|.|:.||..||.|:.|:|:|.:|.|..|.|:|::|||.|.
 Frog   425 -DVTDVLLLDVTPLSLGIETLGGVFTKLIGRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMA 488

  Fly   452 KDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEI 516
            .||.|||.|.|.||||||||||||||.||::|:||::|:|||..||:.::|.|.: .|.|||.:|
 Frog   489 SDNKLLGQFTLVGIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQS-SGGLSKDDI 552

  Fly   517 DRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWL 581
            :.|:..||||..||.|::|||::.||.|               |::.:||
 Frog   553 ENMVKNAEKYAEEDRRRKERVEAVNNAE---------------GIIHDTE--------------- 587

  Fly   582 DKNSLAEKEEFESHL--KECQRICTPIMSKI 610
                 ::.|||:..|  .||.::...| ||:
 Frog   588 -----SKMEEFKDQLPADECNKLKEEI-SKV 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	293/616 (48%)
hspa9	NP_001001229.1	dnaK	46..664	CDD:234715	293/616 (48%)