Protein Alignment Hsc70-2 and Hsc70-1

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 448/642 - (69%)
• Similarity: 529/642 - (82%)
• Gaps: 11/642 - (1%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|:||:|||||||||||||:|:.||||||||||||||||||||.|:||||||.||||||||..|
  Fly     1 MPKLPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |:|||||||||:|||..:|.|:|.|||:|..|.|||:|.||:|||||.|.|||:||||||||||.
  Fly    66 TIFDAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRET 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            ||.||||.|.||||||||||||||||||||||:|||||||||||||||||:||||||....||||
  Fly   131 AEAYLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||||:|::| :|||||||||||||||||||||||||.:||:||||.|:..|.||
  Fly   196 LIFDLGGGTFDVSVLTIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRA 259

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            |||||||||||||||||||:||:|||:|.||:|||:.::||||||||.||||.||:||.:||.||
  Fly   260 LRRLRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDA 324

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            ||||..|||:|||||||||||:|:||||.|.||:||.|||||||||||||||||||.|..|..:|
  Fly   325 KMDKGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQ 389

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            ||||:||.||||||||||||||.|::||..||.||.||||||:|||..|.|||:|||||||:|||
  Fly   390 DLLLLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNN 454

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            .||.|.|:.||||||||||:||.||::|:|||||.|.:.||||..:|||:||||||||.:|:||:
  Fly   455 SLGKFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMV 519

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKN 584
            ::||.|:..|::||:|:.:||.||:|.:..|..:||.. |...|..:|..::.:.|...:|||.|
  Fly   520 NDAEAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDAN 584

  Fly   585 SLAEKEEFESHLKECQRICTPIMSKIHGG-------KKGKSSMGK--GSHPTVEEVD 632
            .|||::|||...:|.:|||:||:::::.|       ..|.|:.|.  ||.||:||||
  Fly   585 QLAERQEFEHKQQELERICSPIITRLYQGAGMAPPPTAGGSNPGATGGSGPTIEEVD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	446/640 (70%)
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	446/640 (70%)