Protein Alignment Hsc70-2 and hsc70

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Alignment Length: 648
• Identity: 454/648 - (70%)
• Similarity: 530/648 - (81%)
• Gaps: 17/648 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|.||:||||||||||||::|:.||||||||||||||||||||.:|||||||.||||||||..|
Zfish     1 MSKGPAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |||||||||||:|||..:|.|:|.||||||::..|||:|||:|||.|.|.|||:||||||||:||
Zfish    66 TVFDAKRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEI 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            :|.|||..|.:||:||||||||||||||||||:|||||||||||||||||:||||||.:.|||||
Zfish   131 SEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|:|::| :||||:|||||||||||||||:||||..|||||.|.||.||.||
Zfish   196 LIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRA 259

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            :||||||||||||||||||:||:|||:|:||.|||:.|:||||||||.||||.|::|||:||.||
Zfish   260 VRRLRTACERAKRTLSSSTQASIEIDSLYEGADFYTSITRARFEELNADLFRGTLEPVEKALRDA 324

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            ||||..|||:||||||||||||||||||.|.|:.||.|||||||||||||||||||||..|..:|
Zfish   325 KMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQ 389

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            ||||:||.||||||||||||||.|::||..||.||.|.||||||||..|.|||||||||||||||
Zfish   390 DLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNN 454

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            :||.|.||||||||||||||||.||::|:|||||:|.|.||||..||||:||||||||.:|:||:
Zfish   455 ILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMV 519

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAV-DDAPSGVLSETERSKVRDKCSSEASWLDKN 584
            .||::|:.||:.|||:|.:||.||:..:..:..| ||.....:|..::..:.|||:...||||||
Zfish   520 QEADQYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPEDKKTITDKCNEVISWLDKN 584

  Fly   585 SLAEKEEFESHLKECQRICTPIMSKIH---------------GGKKGKSSMGKGSHPTVEEVD 632
            ..|||:|:|...||.:::|.||::|::               ||..|....|..|.||:||||
Zfish   585 QTAEKDEYEHQQKELEKVCNPIITKLYQGAGGMPGGMPGGMPGGYPGGQGSGSSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	452/646 (70%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	298/375 (79%)
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	443/611 (73%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	298/375 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H74294
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.730