Protein Alignment Hsc70-2 and hspa5

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_998223.1
• Gene: hspa5 / 378848
• ZFINID: ZDB-GENE-031001-11
• Length: 650
• Species: Danio rerio
• Alignment Length: 630
• Identity: 366/630 - (58%)
• Similarity: 476/630 - (75%)
• Gaps: 17/630 - (2%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF-NETERLIGDPAKNQVAMNAKNTVFDA 70
            ||||||||||||||::|.:|||||||||||.||||||| .|.||||||.||||:..|.:||||||
Zfish    29 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPENTVFDA 93

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEF-KGERKRFAPEEISSMVLTKMREIAEVY 134
            ||||||.:.|..:|:|:|.:|||||.:|.||.|:::. .|:.|.|||||||:||||||:|.||.|
Zfish    94 KRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMKETAEAY 158

  Fly   135 LGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 199
            ||.||..|||||||||||:|||||||||:||||||:||||||||||:||||||. .||:|:|:||
Zfish   159 LGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR-DGEKNILVFD 222

  Fly   200 LGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRL 264
            |||||||||:|:||.| :|||.||.|||||||||||.|::.||.:.:|:|...|::.:.||:::|
Zfish   223 LGGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKL 286

  Fly   265 RTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDK 329
            |...|:|||.||:..:|.:||::..||.||...::||:|||||||||||||:||::.|.|:...|
Zfish   287 RREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDPKK 351

  Fly   330 KAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLL 394
            ..|.::|||||||||||||:|:::.|.||:.:..|||||||||||||||.:|:  |..:..||:|
Zfish   352 PDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLS--GEEETGDLVL 414

  Fly   395 VDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGT 459
            :||.||:|||||.|||||.|:.||..:|.|:.|||:|.||||..|||:||||||.:||||:||||
Zfish   415 LDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGT 479

  Fly   460 FNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAE 524
            |:||||||||||||||||.|:::.:|||.|.|:|..||...||||:||:.||:..:|:||::|||
Zfish   480 FDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNEAE 544

  Fly   525 KYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP--SGVLSETERSKVRDKCSSEASWLDKNSLA 587
            ::..||.:.:||:.|:|.||:|.|:.:..:.|..  .|.||..::..:......:..||:.:..|
Zfish   545 RFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKEAIEKAVEEKIEWLEAHQDA 609

  Fly   588 EKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKGSHPTVEEVD 632
            :.|||::..||.:.:..||:||::|...|         |..||.:
Zfish   610 DLEEFQAKKKELEEVVQPIVSKLYGSAGG---------PPPEEAE 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	366/628 (58%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	246/376 (65%)
hspa5	NP_998223.1	HSPA5-like_NBD	26..401	CDD:212681	245/373 (66%)
		PTZ00009	29..641	CDD:240227	364/624 (58%)
		Periplasmic_Binding_Protein_Type_2	<583..640	CDD:304360	16/65 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830