Protein Alignment Hsc70-2 and hsp70.3

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_571472.2
• Gene: hsp70.3 / 30671
• ZFINID: ZDB-GENE-110713-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 641
• Identity: 459/641 - (71%)
• Similarity: 530/641 - (82%)
• Gaps: 19/641 - (2%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |||||||||||||||:|:.||||||||||||||||||||.:|||||||.||||||||..||||||
Zfish     8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDA 72

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||:|||..:|.|:|.|.|||:::.||||:.||.|||.|.|.|||||||||.||:||||.||
Zfish    73 KRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAEAYL 137

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |.||.:||:||||||||||||||||||.|||||||||||||||||:||||||....|||||||||
Zfish   138 GQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLIFDL 202

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|:|::| :||||||||||||||||||||:||||.||||||||.||..|.|||||||
Zfish   203 GGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRRLR 266

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            |||||||||||||::||:|||:|:||||||:.|:|||||||..||||.|:.|||:||.||||||.
Zfish   267 TACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMDKA 331

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395
            .|||:||||||||||||||||||.|.|::||.|||||||||||||||||||.|..|..:|||||:
Zfish   332 QIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLLLL 396

  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460
            |||||||||||||||||.|::||..||.||.|.||||||||..|.|||:||||||||||||||.|
Zfish   397 DVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNNLLGKF 461

  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525
            .||||||||||||||||.||::|:|||||:|.|.||||..||||:||||||||.||:||:.||:|
Zfish   462 ELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQEADK 526

  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAV-DDAPSGVLSETERSKVRDKCSSEASWLDKNSLAEK 589
            ||.|||.|||::.:||:||:|.:..:.:| ||...|.:||.::.:|.:||:...|||:.|.||:|
Zfish   527 YKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQLADK 591

  Fly   590 EEFESHLKECQRICTPIMSKIH-------------GGKKGKSSMGKGSHPTVEEVD 632
            ||:|..|||.:::|.|::||::             .|..|.|:.|    ||:||||
Zfish   592 EEYEHQLKELEKVCNPVISKLYQGGMPAGGCGAQARGASGASAQG----PTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	457/639 (72%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	301/375 (80%)
hsp70.3	NP_571472.2	PTZ00009	5..643	CDD:240227	457/639 (72%)
		HSPA1-2_6-8-like_NBD	8..383	CDD:212675	301/375 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	O	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830