Protein Alignment Hsc70-2 and ssc1

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_593459.1
• Gene: ssc1 / 2543026
• PomBaseID: SPAC664.11
• Length: 674
• Species: Schizosaccharomyces pombe
• Alignment Length: 649
• Identity: 292/649 - (44%)
• Similarity: 418/649 - (64%)
• Gaps: 53/649 - (8%)

  Fly     3 KIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF-NETERLIGDPAKNQVAMNAKNT 66
            |.|.||||||||.||:.:.:....::|||.:|.|||||.||| .:.|||:|..||.|..:|.:||
pombe    49 KGPVIGIDLGTTTSCLAIMEGQTPKVIANAEGTRTTPSVVAFTKDGERLVGVSAKRQAVINPENT 113

  Fly    67 VFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIA 131
            .|..||||||:|.:.::|.|:|..|:|:: |.......:|.:|  |.::|.:|...:|:||||.|
pombe   114 FFATKRLIGRRFKEPEVQRDIKEVPYKIV-EHSNGDAWLEARG--KTYSPSQIGGFILSKMRETA 175

  Fly   132 EVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVL 196
            ..|||..||:||||||||||||||||||.||:||||||||::||||||||||||||  |.:..|.
pombe   176 STYLGKDVKNAVVTVPAYFNDSQRQATKAAGAIAGLNVLRVVNEPTAAALAYGLDK--KNDAIVA 238

  Fly   197 IFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARAL 261
            :|||||||||:|:|.::.| :|||::|.|||||||||||..||.|..|.||:....|:..:..|:
pombe   239 VFDLGGGTFDISILELNNG-VFEVRSTNGDTHLGGEDFDVALVRHIVETFKKNEGLDLSKDRLAV 302

  Fly   262 RRLRTACERAKRTLSSSTEASLEI-----DAL---HEGIDFYSKISRARFEELNMDLFRSTMQPV 318
            :|:|.|.|:||..|||.::..:.:     ||.   |..::    ||||:||:|...|.|.|:.|.
pombe   303 QRIREAAEKAKCELSSLSKTDISLPFITADATGPKHINME----ISRAQFEKLVDPLVRRTIDPC 363

  Fly   319 ERALSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTG 383
            :|||.||.:....|::|:||||.||:|::.:.::.:| .::...|:|||||||.|||:|..:|:|
pombe   364 KRALKDANLQTSEINEVILVGGMTRMPRVVETVKSIF-KREPAKSVNPDEAVAIGAAIQGGVLSG 427

  Fly   384 VGSSQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGER 448
                .::||:|:||.||||||||.|||.|.|:.||..||.::.|:|:|.:|.|.||.|:|::|||
pombe   428 ----HVKDLVLLDVTPLSLGIETLGGVFTRLINRNTTIPTRKSQVFSTAADGQTAVEIRVFQGER 488

  Fly   449 AMTKDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSK 513
            .:.:||.|:|.|.||||.|||:|.|||||:||::||||:||:|:|.:|.|...||::...| |:.
pombe   489 ELVRDNKLIGNFQLTGIAPAPKGQPQIEVSFDVDADGIINVSARDKATNKDSSITVAGSSG-LTD 552

  Fly   514 AEIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYAC---------------RQAVDDAPSGVLS 563
            :||:.|:::||||:..|..::|.:::.|..|:   .|               :|||:|.
pombe   553 SEIEAMVADAEKYRASDMARKEAIENGNRAES---VCTDIESNLDIHKDKLDQQAVEDL------ 608

  Fly   564 ETERSKVRDKCSSEASWLDKNSLAEKEEFESHLKECQRICTPIMSKIHGGK-KGKSSMGKGSHP 626
               |||:.|...:.|.....:.....|:.:..:.|.|::...:...::..: :|..|.|..|.|
pombe   609 ---RSKITDLRETVAKVNAGDEGITSEDMKKKIDEIQQLSLKVFESVYKNQNQGNESSGDNSAP 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	292/649 (45%)
ssc1	NP_593459.1	dnaK	49..671	CDD:234715	292/649 (45%)