Protein Alignment Hsc70-2 and sks2

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_595438.1
• Gene: sks2 / 2540199
• PomBaseID: SPBC1709.05
• Length: 613
• Species: Schizosaccharomyces pombe
• Alignment Length: 595
• Identity: 340/595 - (57%)
• Similarity: 430/595 - (72%)
• Gaps: 23/595 - (3%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |||||||||||||.||:.:.||||.||||.|||||:|||.|||||:||.||||.|||.:||||||
pombe     8 AIGIDLGTTYSCVAVWETANVEIIPNDQGARTTPSFVAFTETERLVGDAAKNQAAMNPRNTVFDA 72

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||:::|.:.|:|:|.||||||:..|.|.|||.:.||:|:|..:|||:||||||:||:|..|
pombe    73 KRLIGRRYEDPETQKDIKHWPFKVIDNNGIPTIEVNYLGEKKQFTAQEISAMVLTKMKEISEAKL 137

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            ..:|:.||:||||||:||||.||||||:|||||||||||||||||:|||||......:|||||||
pombe   138 NKRVEKAVITVPAYFSDSQRAATKDAGAIAGLNVLRIINEPTAAAIAYGLDAKSDKPKNVLIFDL 202

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|.| :|.:|||.|||||||||||||||.||.||.:|||||.|.||..:.|||||||
pombe   203 GGGTFDVSLLKI-QGGVFEVLATAGDTHLGGEDFDNALVEHFIQEFKRKQKIDISDDPRALRRLR 266

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            :|||||||.|||.|:.::|:|:|..||||.|.|:|||||::|...|::|:.||.:.|.|:|:.|.
pombe   267 SACERAKRALSSVTQTTVEVDSLSNGIDFSSSITRARFEDINATTFKATIDPVAKVLKDSKVPKA 331

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTG-VGSSQIQDLLL 394
            .:||:|||||||||||:|:|:.|.|.|:.||.|||||||||||||||||:||. ..|.:.|||||
pombe   332 DVHDIVLVGGSTRIPKVQRLVSDFFDGRALNKSINPDEAVAYGAAVQAAVLTNKADSDKTQDLLL 396

  Fly   395 VDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGT 459
            :||.|||||:...|.|...:..||..||..:::.|||.:|||..||..||:|||....:|..||.
pombe   397 LDVVPLSLGVAMEGNVFGVVCPRNTPIPTIKKRTFTTVADNQTTVTFPVYQGERVNCAENEPLGE 461

  Fly   460 FNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAE 524
            |.||||||.|||..::|..|:|:|:|||.|.|.:.:||:|..|.|:|..|.||..:|..|:..|:
pombe   462 FQLTGIPPMPRGQAELEATFELDANGILKVTAVEKTTGRSAHIEITNSVGHLSSTKIQEMIENAD 526

  Fly   525 KYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAEK 589
            |:|.:|....:::::|:.||:||......:                     ||.:.:.|....:|
pombe   527 KFKQQDKDFAKKLEAKSQLESYISNIETTI---------------------SEPNVMMKLKRGDK 570

  Fly   590 EEFESHLKEC 599
            .:.|:.|.||
pombe   571 SKIEAQLAEC 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	340/595 (57%)
sks2	NP_595438.1	PTZ00009	5..585	CDD:240227	340/595 (57%)