Protein Alignment Hsc70-2 and hsp-3

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001370435.1
• Gene: hsp-3 / 180880
• WormBaseID: WBGene00002007
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 346/624 - (55%)
• Similarity: 477/624 - (76%)
• Gaps: 10/624 - (1%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF--NETERLIGDPAKNQVAMNAKNTVFD 69
            ||||||||||||||::|.:|||||||||||.|||||||  ::.:|||||.||||:.:|.:||:||
 Worm    36 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFD 100

  Fly    70 AKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVY 134
            |||||||.::||.:|.|:|.||||||::..||.:||:...:.|:|.|||:|:|||.||:||||.|
 Worm   101 AKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESY 165

  Fly   135 LGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 199
            ||.:||:|||||||||||:|||||||||:||||||:||||||||||:||||||. .||||:|:||
 Worm   166 LGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKK-DGERNILVFD 229

  Fly   200 LGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRL 264
            |||||||||:|:||.| :|||.||.|||||||||||.|::.:|.:.:|:|...|::.:.||:::|
 Worm   230 LGGGTFDVSMLTIDNG-VFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKL 293

  Fly   265 RTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDK 329
            |...|:|||.||:..:..:||::|.:|.||...::||:||||||||||:|::||::.|.|:.:.|
 Worm   294 RREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKK 358

  Fly   330 KAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLL 394
            ..:|::|||||||||||:|:|:::.|.||:.:..||||||||||||||..:::  |.....:::|
 Worm   359 DDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVIS--GEEDTGEIVL 421

  Fly   395 VDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGT 459
            :||.||::||||.|||||.|:.||..||.|:.|:|:|.:|||..|||||:||||.|||||:.||.
 Worm   422 LDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGK 486

  Fly   460 FNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAE 524
            |:|||:||||||||||||.|:::.:|||:|.|:|..||...||||:||:.|||..:|:||:::||
 Worm   487 FDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAE 551

  Fly   525 KYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP--SGVLSETERSKVRDKCSSEASWLDKNSLA 587
            |:..:|.:.:::.:::|.||:|.|..:..::|..  .|.|.|.::..:.:......|||..|:.|
 Worm   552 KFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEA 616

  Fly   588 EKEEFESHLKECQRICTPIMSKIH--GGKKGKSSMGKGS 624
            ..||.:...|:.:....||:||::  .|..|:.:..:||
 Worm   617 SAEELKEQKKDLESKVQPIVSKLYKDAGAGGEEAPEEGS 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	346/624 (55%)
hsp-3	NP_001370435.1	PTZ00009	32..648	CDD:240227	343/615 (56%)