Protein Alignment Hsc70-2 and hsp-6

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001370558.1
• Gene: hsp-6 / 178873
• WormBaseID: WBGene00002010
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 635
• Identity: 295/635 - (46%)
• Similarity: 416/635 - (65%)
• Gaps: 28/635 - (4%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFN-ETERLIGDPAKNQVAMNAKNTVFDA 70
            ||||||||.|||.:.:....::|.|.:|.|||||.|||. :.|||:|.|||.|...|:.||:|..
 Worm    34 IGIDLGTTNSCVSIMEGKTPKVIENAEGVRTTPSTVAFTADGERLVGAPAKRQAVTNSANTLFAT 98

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVIN-EKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVY 134
            ||||||:::|.::|:|||:.|:|::. ..|...:|    .:.|.::|.::.:.||.||:|.||.|
 Worm    99 KRLIGRRYEDPEVQKDLKVVPYKIVKASNGDAWVE----AQGKVYSPSQVGAFVLMKMKETAESY 159

  Fly   135 LGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 199
            ||..|.:|||||||||||||||||||||.|:||||||:|||||||||||||||: .|::.:.::|
 Worm   160 LGTTVNNAVVTVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKD-AGDKIIAVYD 223

  Fly   200 LGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRL 264
            |||||||||:|.|.:| :||||:|.|||.|||||||:.||:|...|||::...|:..:.:|::||
 Worm   224 LGGGTFDVSILEIQKG-VFEVKSTNGDTFLGGEDFDHALVHHLVGEFKKEQGVDLTKDPQAMQRL 287

  Fly   265 RTACERAKRTLSSSTEASLEIDAL--------HEGIDFYSKISRARFEELNMDLFRSTMQPVERA 321
            |.|.|:||..|||:|:..:.:..:        |..:    |::||:||::..||.:.|::|..:|
 Worm   288 REAAEKAKCELSSTTQTDINLPYITMDQSGPKHLNL----KLTRAKFEQIVGDLIKRTIEPCRKA 348

  Fly   322 LSDAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGS 386
            |.||::....|.||:||||.:|:||:|..:|::| ||..:.::|||||||.|||:|.|:|.|
 Worm   349 LHDAEVKSSQIADVLLVGGMSRMPKVQATVQEIF-GKVPSKAVNPDEAVAMGAAIQGAVLAG--- 409

  Fly   387 SQIQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMT 451
             .:.|:||:||.||||||||.||:||.|:.||..||.|:.|:|:|.:|.|..|.|:|::|||.|.
 Worm   410 -DVTDVLLLDVTPLSLGIETLGGIMTKLITRNTTIPTKKSQVFSTAADGQTQVQIKVFQGEREMA 473

  Fly   452 KDNNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEI 516
            ..|.|||.|:|.|||||||||||:||.||::|:||:||:|:|..|||.::|.|.: .|.|||.:|
 Worm   474 TSNKLLGQFSLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDRGTGKEQQIVIQS-SGGLSKDQI 537

  Fly   517 DRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWL 581
            :.|:.||||...||.:::|.|:..|..|..|:.....:.:. :..|.:.|...:|.|.:.....|
 Worm   538 ENMIKEAEKNAAEDAKRKELVEVINQAEGIIHDTEAKMTEF-ADQLPKDECEALRTKIADTKKIL 601

  Fly   582 DKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKGSH-PTVEE 630
            |.......|..:......|:....:....:.....|:|.|.... .|.||
 Worm   602 DNKDNETPEAIKEACNTLQQQSLKLFEAAYKNMAAKNSGGDAQEAKTAEE 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	295/635 (46%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	194/384 (51%)
hsp-6	NP_001370558.1	dnaK	30..646	CDD:234715	292/628 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820