Protein Alignment Hsc70-2 and hsp-1

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_503068.1
• Gene: hsp-1 / 178507
• WormBaseID: WBGene00002005
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 453/642 - (70%)
• Similarity: 527/642 - (82%)
• Gaps: 12/642 - (1%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|..|:|||||||||||||:.:.||||||||||||||||||||.:|||||||.||||||||..|
 Worm     1 MSKHNAVGIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKG-KPKIEVEFKGERKRFAPEEISSMVLTKMRE 129
            |||||||||||||||..:|.|:|.||||||:.:| |||::||:|||.|.|.|||||||||.||:|
 Worm    66 TVFDAKRLIGRKFDDPAVQSDMKHWPFKVISAEGAKPKVQVEYKGENKIFTPEEISSMVLLKMKE 130

  Fly   130 IAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERN 194
            .||.:||..||||||||||||||||||||||||:|||||||||||||||||:||||||...||||
 Worm   131 TAEAFLGTTVKDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGHGERN 195

  Fly   195 VLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNAR 259
            ||||||||||||||:|:|::| :||||:|||||||||||||||:||||..|||||||.|:..|.|
 Worm   196 VLIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFCAEFKRKHKKDLASNPR 259

  Fly   260 ALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSD 324
            |||||||||||||||||||::||:|||:|.||||||:.|:|||||||..|||||||.|||::|.|
 Worm   260 ALRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTNITRARFEELCADLFRSTMDPVEKSLRD 324

  Fly   325 AKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQI 389
            |||||..:||:|||||||||||:||||.|||.||:||.|||||||||||||||||||:|..|..:
 Worm   325 AKMDKSQVHDIVLVGGSTRIPKVQKLLSDLFSGKELNKSINPDEAVAYGAAVQAAILSGDKSEAV 389

  Fly   390 QDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDN 454
            |||||:|||||||||||||||||.|::||..||.|..|.||||||||..|.||||||||||||||
 Worm   390 QDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKTAQTFTTYSDNQPGVLIQVYEGERAMTKDN 454

  Fly   455 NLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRM 519
            ||||.|.|:||||||||||||||.||::|:|||||:|.|.||||..||||:||||||||.:|:||
 Worm   455 NLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSATDKSTGKQNKITITNDKGRLSKDDIERM 519

  Fly   520 LSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDK 583
            ::||||||.:|:.|::|:.:||.||:|.:..:|.::|.. ...:|..::.|:.|||.....|||.
 Worm   520 VNEAEKYKADDEAQKDRIGAKNGLESYAFNLKQTIEDEKLKDKISPEDKKKIEDKCDEILKWLDS 584

  Fly   584 NSLAEKEEFESHLKECQRICTPIMSKIH--------GGKKGKSSMGKGSHPTVEEVD 632
            |..|||||||...|:.:.:..||:||::        |...|.::.|.|. ||:||||
 Worm   585 NQTAEKEEFEHQQKDLEGLANPIISKLYQSAGGAPPGAAPGGAAGGAGG-PTIEEVD 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	451/640 (70%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	300/376 (80%)
hsp-1	NP_503068.1	PTZ00009	1..614	CDD:240227	443/613 (72%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	300/376 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	O	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.830