Protein Alignment Hsc70-2 and F44E5.5

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_496510.1
• Gene: F44E5.5 / 174806
• WormBaseID: WBGene00009692
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 427/648 - (65%)
• Similarity: 520/648 - (80%)
• Gaps: 19/648 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |....||||||||||||||::||.||||:||.:||:||||||||.:||||:||.||:|.|.|.:|
 Worm     1 MSSCKAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPEN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |||||||||||:||:..:|.|.|.|||.|..::|||.||||.|||:::|.|||||:|||.||:|.
 Worm    66 TVFDAKRLIGRRFDESTVQSDCKHWPFGVKGKQGKPVIEVEVKGEKRQFNPEEISAMVLQKMKET 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            ||.|||..|||||:|||||||||||||||||.:|||||.:|||||||||||||||||.::.|:||
 Worm   131 AETYLGHTVKDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGIQDEKNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|||.|||:||||:|||||||||||||.|::.||..|||||...||..|.||
 Worm   196 LIFDLGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDQRMLQHFMNEFKRKTGKDISPNPRA 260

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            :|||||||||||||||||:||.:|:|:|.||||..:||:|||||||..||||.|::|||:||.||
 Worm   261 IRRLRTACERAKRTLSSSSEACVEVDSLFEGIDLCTKITRARFEELCADLFRKTLEPVEKALRDA 325

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            |:||..|.:|||||||||:|||||||:|.|.||:||.|||||||||:|||||||:|:||....|:
 Worm   326 KLDKSKIDEVVLVGGSTRVPKIQKLLKDFFNGKELNCSINPDEAVAFGAAVQAAVLSGVKDETIK 390

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            |:||||||||||||||||||||||::||.|||.|..:.||||:|||..|:|||||||||||:||:
 Worm   391 DVLLVDVAPLSLGIETAGGVMTNLIDRNTRIPTKACKTFTTYADNQPGVSIQVYEGERAMTRDNH 455

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            .||||.|:||||||||||||||.||::|:|||||:|:|.|||||.:|||.|:||||::::||||:
 Worm   456 RLGTFELSGIPPAPRGVPQIEVTFDIDANGILNVSAEDKSTGKSNRITIQNEKGRLTQSDIDRMV 520

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNS 585
            .||::::.||..||||||::|.||||.:..:||:|:. |..||..:.|:.::.......|||.||
 Worm   521 HEAKQFEKEDGEQRERVQARNQLEAYAFQIKQALDEY-SSKLSTEDASRAKEAVDETLRWLDSNS 584

  Fly   586 LAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKG----------------SHPTVEEVD 632
            ||||:|.|:..||.:.:|..|::|:|  :.|:||...|                ..|||||||
 Worm   585 LAEKDEIEAKDKELKSVCQSILTKMH--QSGQSSASAGCAGNPGTAGFNPNNYPQGPTVEEVD 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	425/646 (66%)
F44E5.5	NP_496510.1	PTZ00009	1..645	CDD:240227	425/646 (66%)