Protein Alignment Hsc70-2 and F44E5.4

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_496509.1
• Gene: F44E5.4 / 174805
• WormBaseID: WBGene00009691
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 427/648 - (65%)
• Similarity: 520/648 - (80%)
• Gaps: 19/648 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |....||||||||||||||::||.||||:||.:||:||||||||.:||||:||.||:|.|.|.:|
 Worm     1 MSSCKAIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPEN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |||||||||||:||:..:|.|.|.|||.|..::|||.||||.|||:::|.|||||:|||.||:|.
 Worm    66 TVFDAKRLIGRRFDESTVQSDCKHWPFGVKGKQGKPVIEVEVKGEKRQFNPEEISAMVLQKMKET 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            ||.|||..|||||:|||||||||||||||||.:|||||.:|||||||||||||||||.::.|:||
 Worm   131 AETYLGHTVKDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGIQDEKNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|||.|||:||||:|||||||||||||.|::.||..|||||...||..|.||
 Worm   196 LIFDLGGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDQRMLQHFMNEFKRKTGKDISPNPRA 260

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            :|||||||||||||||||:||.:|:|:|.||||..:||:|||||||..||||.|::|||:||.||
 Worm   261 IRRLRTACERAKRTLSSSSEACVEVDSLFEGIDLCTKITRARFEELCADLFRKTLEPVEKALRDA 325

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            |:||..|.:|||||||||:|||||||:|.|.||:||.|||||||||:|||||||:|:||....|:
 Worm   326 KLDKSKIDEVVLVGGSTRVPKIQKLLKDFFNGKELNCSINPDEAVAFGAAVQAAVLSGVKDETIK 390

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            |:||||||||||||||||||||||::||.|||.|..:.||||:|||..|:|||||||||||:||:
 Worm   391 DVLLVDVAPLSLGIETAGGVMTNLIDRNTRIPTKACKTFTTYADNQPGVSIQVYEGERAMTRDNH 455

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            .||||.|:||||||||||||||.||::|:|||||:|:|.|||||.:|||.|:||||::::||||:
 Worm   456 RLGTFELSGIPPAPRGVPQIEVTFDIDANGILNVSAEDKSTGKSNRITIQNEKGRLTQSDIDRMV 520

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNS 585
            .||::::.||..||||||::|.||||.:..:||:|:. |..||..:.|:.::.......|||.||
 Worm   521 HEAKQFEKEDGEQRERVQARNQLEAYAFQIKQALDEY-SSKLSTEDASRAKEAVDETLRWLDSNS 584

  Fly   586 LAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKG----------------SHPTVEEVD 632
            ||||:|.|:..||.:.:|..|::|:|  :.|:||...|                ..|||||||
 Worm   585 LAEKDEIEAKDKELKSVCQSILTKMH--QSGQSSASAGCAGNPGTAGFNPNNYPQGPTVEEVD 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	425/646 (66%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	276/375 (74%)
F44E5.4	NP_496509.1	PTZ00009	1..645	CDD:240227	425/646 (66%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	276/375 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730