Protein Alignment Hsc70-2 and hsp-4

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_001370395.1
• Gene: hsp-4 / 174203
• WormBaseID: WBGene00002008
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 633
• Identity: 353/633 - (55%)
• Similarity: 483/633 - (76%)
• Gaps: 16/633 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAF--NETERLIGDPAKNQVAMNA 63
            ||.|  ||||||||||||||::|.:|||||||||||.|||||||  ::.||||||.||||:.:|.
 Worm    29 MGTI--IGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDQGERLIGDAAKNQLTINP 91

  Fly    64 KNTVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMR 128
            :||:|||||||||.:::|.:|:|:|.||||::::..||.:||:...|.|:|.|||:|:||||||:
 Worm    92 ENTIFDAKRLIGRFYNEKTVQQDIKHWPFKIVDKSNKPNVEVKVGSETKQFTPEEVSAMVLTKMK 156

  Fly   129 EIAEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGER 193
            :|||.|||.:||:|||||||||||:|:||||||||||||||:||||||||||:||||||. .|||
 Worm   157 QIAESYLGHEVKNAVVTVPAYFNDAQKQATKDAGSIAGLNVVRIINEPTAAAIAYGLDKK-DGER 220

  Fly   194 NVLIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNA 258
            |:|:|||||||||||:|:||.| :|||.||.|||||||||||.|::.:|.:.:|:|...|::.:.
 Worm   221 NILVFDLGGGTFDVSLLTIDSG-VFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDN 284

  Fly   259 RALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALS 323
            ||:::||...|:|||.||:..:..:||::|.:|.||...::||:||||||||||:|::||::.|.
 Worm   285 RAVQKLRREVEKAKRALSTQHQTKIEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLE 349

  Fly   324 DAKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQ 388
            ||.|.|..:|::|||||||||||:|:|::|.|.||:.:..|||||||||||||||.::.||.::
 Worm   350 DADMKKTDVHEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGINPDEAVAYGAAVQAGVIGGVENT- 413

  Fly   389 IQDLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKD 453
             .|::|:||.||:|||||.|||||.|:.||..||.|:.|:|:|.:|:|:||:|.:|||||.|..|
 Worm   414 -GDVVLLDVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADSQSAVSIVIYEGERPMVMD 477

  Fly   454 NNLLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDR 518
            |:.||.|::|||||||||||||||.|:::.:|||:|:|:|..||...|:||:||..|||..:|:|
 Worm   478 NHKLGNFDVTGIPPAPRGVPQIEVTFEIDVNGILHVSAEDKGTGNKNKLTITNDHNRLSPEDIER 542

  Fly   519 MLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP--SGVLSETERSKVRDKCSSEASWL 581
            |:::|:|:..:|..|:|:|:|:|.||||.|..:..:.|..  .|.|::.::..:.........||
 Worm   543 MINDADKFAADDQAQKEKVESRNELEAYAYQMKTQIADKEKLGGKLTDEDKVSIESAVERAIEWL 607

  Fly   582 DKNSLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMGKGSHPTVE 629
            ..|..|..||.:...||.:.:..||:||::      |:.|:|...:.|
 Worm   608 GSNQDASTEENKEQKKELESVVQPIVSKLY------SAGGQGEQASEE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	353/633 (56%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	240/377 (64%)
hsp-4	NP_001370395.1	PTZ00009	33..643	CDD:240227	348/619 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730