Protein Alignment Hsc70-2 and Hsc70Cb

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_061509666.1
• Gene: Hsc70Cb / 1275989
• VectorBaseID: AGAMI1_015163
• Length: 843
• Species: Anopheles gambiae
• Alignment Length: 727
• Identity: 212/727 - (29%)
• Similarity: 355/727 - (48%)
• Gaps: 111/727 - (15%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDAK 71
            ||||.|...|.|.|.:...:|.||||...|.|||:|||....|::|..||||...|..||:.:.|
Mosquito     4 IGIDFGNDSSYVAVAKAGGIETIANDYSLRATPSFVAFAGRNRVLGVAAKNQQVTNMNNTIGNFK 68

  Fly    72 RLIGRKFDDKKIQEDLKLWPFKV-INEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            .|:||||||.:.||:|:..|:.. ..:.|...|.|.:..|...|:||:|::|:.||::|.|...|
Mosquito    69 ELLGRKFDDPRAQEELRSLPYHTEALQDGGIGIRVNYLDEEHVFSPEQITAMLFTKLKEDAFKEL 133

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKN-----LKGERNV 195
            ..::.|.|:|||:||.::||||..||.:|:||||||::||.||.||:||..|.     .:..|||
Mosquito   134 KTQINDCVITVPSYFTNAQRQALLDAANISGLNVLRLMNETTATALSYGFYKQDLPAPEEKPRNV 198

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            :..|.|..:..||..:..:|:| ::.|:..|: :||.|||..|..||.:||:.|:|.|.....||
Mosquito   199 IFVDCGHASLQVSACAFHKGNL-KMLASCSDS-VGGRDFDLVLATHFNKEFQTKYKIDASSKKRA 261

  Fly   261 LRRLRTACERAKRTLS-SSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSD 324
            ..||....|:.|:.:| :||:..|.|:.....||.:|.:.|:..|||:..||:.....:.:.|.|
Mosquito   262 FLRLMAEVEKLKKNMSANSTKLPLNIECFMNEIDVHSSMQRSEMEELSSHLFKRIETTMRKLLLD 326

  Fly   325 AKMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQI 389
            :|:..:.||.|.:||||:|||.|:.|::.:| ||..:.::|.||||:.|||:|.|||:  .:.::
Mosquito   327 SKLALEEIHSVEIVGGSSRIPAIKHLIEQIF-GKPASTTLNQDEAVSRGAALQCAILS--PAVRV 388

  Fly   390 QDLLLVDVAPLSLGI---ETAGGVMTNLVERNARIP-CKQQQIFTTYSDNQNAVTIQVYEGERAM 450
            ::....||....:.|   :|.|.....:.|:....| |:   :.|.:  .:..:||:|:....::
Mosquito   389 REFSCTDVQAYPVLISWTDTDGPHEMKVFEQYHAAPFCR---LLTVH--RKEPMTIKVHYEPNSI 448

  Fly   451 TKDNNLLGTFNLTGIPPAPRGVPQ-IEVAFDLNADGILNVNA----------------------- 491
            ...:..:||:::.||.|...|..| ::|...:|.:||:.|::
Mosquito   449 PYPDPFIGTYHVKGIKPDANGEAQEVKVKVRINNNGIITVSSATMYERKESEEPSSPTPTSNGDQ 513

  Fly   492 -----------------------------------KDNS-------------------------T 496
                                               ||:.                         |
Mosquito   514 QKTGDANQSSPQGDESGKVGEPMDIQEGSDDEHPKKDSKPNDSSGEGWTQRVTRWFTSDKKKKVT 578

  Fly   497 GKSEKITISNDKGRLSKAEIDRMLSEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAV--DDAPS 559
            .|..::||.::.......|:.:...|..|....|.:::||:.::|.||..:|..|:.:  |.|..
Mosquito   579 TKQVELTIDSNTHGFVHTELCKYFEEEMKMIANDRQEKERIDARNALEEQVYEIREKIQEDGALH 643

  Fly   560 GVLSETERSKVRDKCSSEASWL-DKNSLAEKEEFESHLKECQRICTPIMSK---IHGGKKGKSSM 620
            ..:...:.|.:..:.....:|| ::....||..::..|::.:....|:.::   .:|.::..:.:
Mosquito   644 DYIDPQDASAICRELEETENWLYEEGESCEKGVYKERLEKMRAKIDPVRNRCEEFNGQEQAFTDL 708

  Fly   621 GKGSHPTVEEVD 632
            |.....|::.|:
Mosquito   709 GHAVQQTLKAVE 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	211/725 (29%)
Hsc70Cb	XP_061509666.1	None