Protein Alignment Hsc70-2 and LOC1275756

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_315042.3
• Gene: LOC1275756 / 1275756
• VectorBaseID: AGAMI1_000862
• Length: 647
• Species: Anopheles gambiae
• Alignment Length: 648
• Identity: 446/648 - (68%)
• Similarity: 534/648 - (82%)
• Gaps: 17/648 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|.||:|||||||||||||:|:.||:|||||||||||||||||.::||||||.||||||||..|
Mosquito     1 MAKTPAVGIDLGTTYSCVGVFQHGKVDIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPNN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |:|||||||||||||..:|.|:|.|||.||::.||||::||:|||:|.|.|||:||||||||:|.
Mosquito    66 TIFDAKRLIGRKFDDATVQADMKHWPFDVISDGGKPKLQVEYKGEKKSFFPEEVSSMVLTKMKET 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            ||.|||..:.:||:||||||||||||||||||:|||||||||||||||||:||||||...|||||
Mosquito   131 AEAYLGKSIANAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGAGERNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|:|::| :||||:|||||||||||||||:|:||.||||||||.||..|.||
Mosquito   196 LIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVSHFVEEFKRKHKKDITSNKRA 259

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            ||||||||||||||||:||:||:|||:|:||||||:.|:||||||||.||||.||:||.:||.||
Mosquito   260 LRRLRTACERAKRTLSASTQASIEIDSLYEGIDFYTSITRARFEELNSDLFRDTMEPVSKALRDA 324

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            ||||.:|||:|||||||||||:||||||.|.||:||.|||||||||||||||||||.|..|..:|
Mosquito   325 KMDKASIHDIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILQGDTSEAVQ 389

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            ||||:||.||||||||||||||.|::||..||.||.|.||||||||..|.|||:|||||||||||
Mosquito   390 DLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNN 454

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            |||.|.|:||||||||||||||.||::|:||:||:|.:.||.|..:|||:||||||||.:||||:
Mosquito   455 LLGKFELSGIPPAPRGVPQIEVTFDIDANGIMNVSAIEKSTNKENRITITNDKGRLSKEDIDRMV 519

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKN 584
            :||||::.||::|||::.:||:||||.:..:..::||. ...:.:.:::.:.|||::..:|||.|
Mosquito   520 NEAEKFRNEDEKQREKISAKNSLEAYCFNMKSTMEDANIKDKIPDADKTLIMDKCNATIAWLDGN 584

  Fly   585 SLAEKEEFESHLKECQRICTPIMSKIHGGKKGKSSMG---------------KGSHPTVEEVD 632
            ..|||||||...||.:.:|.||:.|::.|..|....|               .|:.||:||||
Mosquito   585 QTAEKEEFEHKQKELEAVCNPIIQKLYQGAGGMPGGGMPGGGMPGAGGAPPTSGAGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	444/646 (69%)
LOC1275756	XP_315042.3	PTZ00009	1..647	CDD:240227	444/646 (69%)