Protein Alignment Hsc70-2 and hspa5

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_002941690.1
• Gene: hspa5 / 100492570
• XenbaseID: XB-GENE-480060
• Length: 655
• Species: Xenopus tropicalis
• Alignment Length: 610
• Identity: 361/610 - (59%)
• Similarity: 469/610 - (76%)
• Gaps: 7/610 - (1%)

  Fly     7 IGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFN-ETERLIGDPAKNQVAMNAKNTVFDA 70
            :|||||||||||||::|.:|||||||||||.|||||||. |.||||||.||||:..|.:||||||
 Frog    33 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA 97

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            ||||||.::|..:|:|:|..|||||..|.||.|:|:...:.|.|||||||:|||.||:|.||.||
 Frog    98 KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYL 162

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |.||..|||||||||||:|||||||||:||||||:||||||||||:||||||. :||:|:|:|||
 Frog   163 GKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKK-EGEKNILVFDL 226

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|:||.| :|||.||.|||||||||||.|::.||.:.:|:|...|::.:.||:::||
 Frog   227 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLR 290

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            ...|:|||.|||..::.:||::..||.||...::||:|||||||||||||:||::.|.||.:.|.
 Frog   291 REVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKS 355

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395
            .|.::|||||||||||||:|:::.|.||:.:..|||||||||||||||.:|:  |.....||:|:
 Frog   356 DIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLS--GDQDTGDLVLL 418

  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460
            ||.||:|||||.|||||.|:.||..:|.|:.|||:|.||||..|||:||||||.:||||:|||||
 Frog   419 DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTF 483

  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525
            :||||||||||||||||.|:::.:|||.|.|:|..||...||||:||:.||:..||:||:::|||
 Frog   484 DLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEK 548

  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP--SGVLSETERSKVRDKCSSEASWLDKNSLAE 588
            :..||.:.:||:.::|.||:|.|:.:..:.|..  .|.||..::..:......:..||:.:..::
 Frog   549 FAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSD 613

  Fly   589 KEEFESHLKECQRICTPIMSKIHGG 613
            .|||::..||.:.|..||:.|::||
 Frog   614 IEEFKAKKKELEEIVQPIVGKLYGG 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	361/610 (59%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	245/375 (65%)
hspa5	XP_002941690.1	HSP70	32..636	CDD:365808	359/606 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010