Protein Alignment Hsc70-2 and hspa12a

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_002941887.2
• Gene: hspa12a / 100489323
• XenbaseID: XB-GENE-959285
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 146/653 - (22%)
• Similarity: 235/653 - (35%)
• Gaps: 203/653 - (31%)

  Fly     7 IGIDLGTTYS-----------CVGV---WQNSKVEIIANDQG--NRTTPSYVAFNETERLIGDPA 55
            :.||.|||.|           |:.:   |:       ..|.|  |:.||:      |..|:.|..
 Frog    56 VAIDFGTTSSGYAYSFSKEPECIHIMRRWE-------GGDPGVSNQKTPT------TMLLMPDRK 107

  Fly    56 KNQVAMNAKNTVFDAKRLIGRKFDDKKIQEDLKLWPFKV-INEKGKPKIEVEFKGER-KRFAPEE 118
            .:.....|::...|        .|..:.:..|....||: ::......:|.|..... ||....|
 Frog   108 FHSFGFAARDFYHD--------LDPSESKHWLYFEKFKMKLHSSTDLTMETELTAANGKRVKALE 164

  Fly   119 ISSMVLTKMREIAEVYL----GGKVKDA----VVTVPAYFNDSQRQATKDAGSIAGL------NV 169
            |.:..|...:|.|...|    |.::..|    |:||||.:....:|..:.|...||:      ..
 Frog   165 IFAYALQYFKEQALKELSDQAGSEMDSAEVRWVITVPAIWKQPAKQFMRQAAYKAGMATPENPEQ 229

  Fly   170 LRIINEPTAA------------------ALAYGLD-----KNL---------------------- 189
            |.|..||..|                  |...|:.     |:|
 Frog   230 LIIALEPEGASIYCRKLRLHQMIDLSSKAAINGISPTDPAKDLARRNRQSRTFLVENVIGELWSE 294

  Fly   190 --KGERNVLIFDLGGGTFDVSV--LSIDEGSLFEVKATAGDTH--LGGE-DFDNRLVNHFAEEFK 247
              :|:|.|:: |.||||.|::|  :.:.||.|.|:...:|..:  ||.: :|:..|...|.::|.
 Frog   295 LEEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSLGVDYEFEKLLCKIFGDDFI 358

  Fly   248 RKHKSDIKGNARALRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFE-------- 304
            ...|  :|..| |...|..|.|..||..:......|.|......||:|.|......|
 Frog   359 DTFK--VKRPA-AWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKSNV 420

  Fly   305 -----------ELNMD----LFRSTMQPVERALSD--AKMDKKAIHDVVLVGGSTRIPKIQKLLQ 352
                       .:|.|    ||:.|:.|:.:.|::  .|.:...:..:.||||....|.:|:.:|
 Frog   421 DFVKWSSQGMLRMNPDAMNALFKPTIDPIIQHLTNLFQKPEVAGVKFLFLVGGFAESPLLQQAVQ 485

  Fly   353 DLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLVDVAPLSLGIETAGGVMTNLVE- 416
            ..| |.|..:.|..|..:   ..::.|:|.|:..:    |:.|..:||:.|:    ||:...||
 Frog   486 QAF-GDQCRVIIPHDVGL---TILKGAVLFGLDPA----LIKVRRSPLTYGV----GVLNRYVEG 538

  Fly   417 ------------------------------------RNARIPCKQQQ------IFTTYSDNQNAV 439
                                                :.:..|.||.|      |:::..|:.|.:
 Frog   539 KHPPEKLLLKDGTRWCTDVFDKFILADQSVALGETVKRSYTPAKQSQLIIIIHIYSSEQDDANFI 603

  Fly   440 TIQVYEGERAMTKDNNLLGTFNLTGIPPAPRGVP---QIEVAFDLNADGILNVNAKDNSTGKSEK 501
            |      ::.:.|...|  ..:|||...||  ||   :|:..... .|..:...|.|.:|.|:.|
 Frog   604 T------DKGVRKCGTL--RLDLTGPESAP--VPSRREIQTIMQF-GDTEIKATAVDVATSKNVK 657

  Fly   502 ITI 504
            ::|
 Frog   658 VSI 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	146/653 (22%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	110/483 (23%)
hspa12a	XP_002941887.2	HSPA12A_like_NBD	54..513	CDD:212685	111/485 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910