Protein Alignment Hsc70-2 and hspa1a

DIOPT Version :9

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_012823021.1
• Gene: hspa1a / 100488052
• XenbaseID: XB-GENE-5842877
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 649
• Identity: 450/649 - (69%)
• Similarity: 533/649 - (82%)
• Gaps: 18/649 - (2%)

  Fly     1 MGKIPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKN 65
            |.|.||:|||||||||||||:|:.||||||||||||||||||||.:|||||||.||||||||..|
 Frog     1 MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65

  Fly    66 TVFDAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREI 130
            |||||||||||:|||..:|.|:|.|||.|||:.|:||::||:|||.|.|..||:||||||||:||
 Frog    66 TVFDAKRLIGRRFDDPVVQSDMKHWPFTVINDGGRPKVQVEYKGEAKTFYAEEVSSMVLTKMKEI 130

  Fly   131 AEVYLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNV 195
            :|.|||..:.:||:||||||||||||||||||:|:|||||||||||||||:||||||.:.|||||
 Frog   131 SEAYLGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGGERNV 195

  Fly   196 LIFDLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARA 260
            |||||||||||||:|:|::| :||||:|||||||||||||||:||||..|||||||.||..|.||
 Frog   196 LIFDLGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFVGEFKRKHKKDITENKRA 259

  Fly   261 LRRLRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDA 325
            :||||||||||||||||||:||:|||:|:||||||:.::||||||||.||||.|::|||:||.||
 Frog   260 IRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSLTRARFEELNADLFRGTLEPVEKALRDA 324

  Fly   326 KMDKKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQ 390
            ||||..|||:||||||||||||||||||.|.|::||.|||||||||||||||||||:|..|..:|
 Frog   325 KMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILSGDKSENVQ 389

  Fly   391 DLLLVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNN 455
            ||||:||.||||||||||||||.|::||..||.||.|.||||||||..|.|||:|||||||||||
 Frog   390 DLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVFEGERAMTKDNN 454

  Fly   456 LLGTFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRML 520
            |||.|.||||||||||||||||.||::|:||:||:|.|.||||..||||:||||||||.||:||:
 Frog   455 LLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEEIERMV 519

  Fly   521 SEAEKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKN 584
            .||::||.||:.|||::.:||:||:..:..:..|:|.. ...:|..::.|:.|||:...||||:|
 Frog   520 QEADRYKAEDEVQREKISAKNSLESLAFNMKSTVEDEKLKDKISPEDKQKILDKCNEVISWLDRN 584

  Fly   585 SLAEKEEFESHLKECQRICTPIMSKIHGGKKGK----------------SSMGKGSHPTVEEVD 632
            .:|||||:|...||.|.:|.||::|::.|..|.                :..|..|.||:||||
 Frog   585 QMAEKEEYEHQQKELQNLCNPIITKLYQGAGGAGMPGGMPGGFPGAGAGAGGGGSSGPTIEEVD 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	448/647 (69%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	295/375 (79%)
hspa1a	XP_012823021.1	PTZ00009	1..612	CDD:240227	440/611 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930