Protein Alignment Hsc70-2 and hspa1b

DIOPT Version :10

• Sequence 1: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: XP_002937685.2
• Gene: hspa1b / 100485441
• XenbaseID: XB-GENE-5915622
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 450/638 - (70%)
• Similarity: 531/638 - (83%)
• Gaps: 12/638 - (1%)

  Fly     6 AIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVFDA 70
            |||||||||||||||:|:.||||||||||||||||||||.:|||||||.||||||:|..||||||
 Frog     7 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPHNTVFDA 71

  Fly    71 KRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEVYL 135
            |||||||:|:..:|.|:|.||||||::.||||:.||:|||.|.|:||||||||||||:|.||.||
 Frog    72 KRLIGRKYDEPVVQSDMKHWPFKVISDGGKPKVTVEYKGEGKSFSPEEISSMVLTKMKETAEAYL 136

  Fly   136 GGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 200
            |.||.:||:||||.|||||||||||||.|||||||||||||||||:||||||:.:||||:|||||
 Frog   137 GYKVTNAVITVPAXFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKSGRGERNILIFDL 201

  Fly   201 GGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRRLR 265
            ||||||||:|:||:| :||||||||||||||||||||:||||.||||||||.||..|.|||||||
 Frog   202 GGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISPNKRALRRLR 265

  Fly   266 TACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMDKK 330
            ||||||||||||||:||:|||:|.||||||:.|:|||||||..||||.|::|||:|:.|||:||.
 Frog   266 TACERAKRTLSSSTQASIEIDSLFEGIDFYTSITRARFEELCADLFRGTLEPVEKAMRDAKLDKS 330

  Fly   331 AIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLLLV 395
            .||::|||||||||||:||||||.|.||:||.|||||||||||||||||||.|..|..:|||||:
 Frog   331 QIHEIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLL 395

  Fly   396 DVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLGTF 460
            ||||||||:||||||||.|::||..||.||.|.||||||||..|.||||||||||||||||||.|
 Frog   396 DVAPLSLGLETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKF 460

  Fly   461 NLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEAEK 525
            :||||||||||||||||.||::|:|||||:|.|.|:||..||||:||||||||.||:|||.||:|
 Frog   461 DLTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSSGKQNKITITNDKGRLSKEEIERMLQEADK 525

  Fly   526 YKVEDDRQRERVQSKNNLEAYIYACRQAVDDAP-SGVLSETERSKVRDKCSSEASWLDKNSLAEK 589
            ||.:|::|||::.:||:||:|.:..:..|:|.. ...:|:.::..:.|||....|||::|.||||
 Frog   526 YKADDEQQREKIAAKNSLESYAFNMKSTVEDNNIKDKISDNDKKSILDKCQEVISWLEQNQLAEK 590

  Fly   590 EEFESHLKECQRICTPIMSKIH---------GGKKGKSSMGKGSH-PTVEEVD 632
            ||:....||.:::|.||::|::         ||..|.....:... ||:||||
 Frog   591 EEYTHKQKELEKLCNPIITKLYQGGMPGGMPGGMPGAGCTAEPKQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	448/636 (70%)
hspa1b	XP_002937685.2	PTZ00009	2..643	CDD:240227	448/636 (70%)