Protein Alignment CG11670 and GZMK

DIOPT Version :10

• Sequence 1: NP_001368950.1
• Gene: CG11670 / 41608
• FlyBaseID: FBgn0038114
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 75/269 - (27%)
• Similarity: 118/269 - (43%)
• Gaps: 41/269 - (15%)

  Fly   167 HDDFN----GRSIVAPGQYPHMAALGFRNENHEIDYKCGGSLISEEFVLTAAHC--LTTHGTSPD 225
            |..||    |...|:|...|.||::.:  ..|.:   |||.||..::|||||||  ..|.|.||.
Human    20 HVCFNMEIIGGKEVSPHSRPFMASIQY--GGHHV---CGGVLIDPQWVLTAAHCQYRFTKGQSPT 79

  Fly   226 IVKIGDIKLKEWELNVAPQRRRVAQIYLHPLYNASLNYHDIGLIQLNRPVEYTWFVRPVRLWPMN 290
            :| :|...|.:.|  .:.|...:.:........:....:||.|::|....:....|:.:.:....
Human    80 VV-LGAHSLSKNE--ASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKT 141

  Fly   291 DIPYG-KLHTMGYGSTGFAQPQ----TNILTELDLSVVPIEQCNSSLPADEGSPHGLLTSQICAH 350
            .:..| |....|:|:|   .|.    ::.|.|:.::|:..:.|||. ....|.|. :....:||.
Human   142 SLRSGTKCKVTGWGAT---DPDSLRPSDTLREVTVTVLSRKLCNSQ-SYYNGDPF-ITKDMVCAG 201

  Fly   351 DYEKNRDTCQGDSGGPLQLNLERRRRRHTSRKHYRYYLVGITSYGAYCR-SELPGVYTRVS-SYI 413
            |.:..:|:|:|||||||..               :.....|.|.|..|. :..||:||.:: .|.
Human   202 DAKGQKDSCKGDSGGPLIC---------------KGVFHAIVSGGHECGVATKPGIYTLLTKKYQ 251

  Fly   414 DWIASIVWP 422
            .||.|.:.|
Human   252 TWIKSNLVP 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11670	NP_001368950.1	Tryp_SPc	172..419	CDD:238113	70/255 (27%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	70/257 (27%)