Protein Alignment CG11670 and CFD

DIOPT Version :10

• Sequence 1: NP_001368950.1
• Gene: CG11670 / 41608
• FlyBaseID: FBgn0038114
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 79/258 - (30%)
• Similarity: 116/258 - (44%)
• Gaps: 43/258 - (16%)

  Fly   172 GRSIVAPGQYPHMAALGFRNENHEIDYKCGGSLISEEFVLTAAHCLTTHGTSPDIVKIGDIKLKE 236
            ||...|..: |:||::.....     :.|||.|::|::||:|||||.........|.:|...|.:
Human    36 GREAEAHAR-PYMASVQLNGA-----HLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQ 94

  Fly   237 WELNVAPQRR--RVAQIYLHPLYNASLNYHDIGLIQLNRPVEYTWFVRPVRLWPM--NDIPYGKL 297
            .|    |.:|  .|.:...||........||:.|:||:........|||:. |..  .|:..|.|
Human    95 PE----PSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLP-WQRVDRDVAPGTL 154

  Fly   298 -HTMGYGSTGFAQPQTNILTELDLSVVPIEQCNSSLPADEGSPHGLLTSQI-CAHDYEKN-RDTC 359
             ...|:|....|..:.:.|..:.|.|:....||.....|     |.:|.:: ||   |.| ||:|
Human   155 CDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHD-----GAITERLMCA---ESNRRDSC 211

  Fly   360 QGDSGGPLQLNLERRRRRHTSRKHYRYYLVGITSYGA-YC-RSELPGVYTRVSSYIDWIASIV 420
            :|||||||...               ..|.|:.:.|: .| ..:.||:||||:||..||.|::
Human   212 KGDSGGPLVCG---------------GVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11670	NP_001368950.1	Tryp_SPc	172..419	CDD:238113	78/255 (31%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	78/255 (31%)