DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment snk and CG14642

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	290	Identity:	111/290 - (38%)
Similarity:	147/290 - (50%)	Gaps:	38/290 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 QEYNAAARRLHLTDTG-------RTFSGKQCVPSVPLIVGGTPTRHGLFPHMAALGWTQGSGSKD 213
            |:|:....|:...||.       ..|.|:            ...|.|.:|||||:|:....|..|
  Fly   119 QKYSEYVERIFPNDTAVAADANDADFDGR------------VLARPGEYPHMAAVGFESDRGQVD 171

  Fly   214 QDIKWGCGGALVSELYVLTAAHCATSGSKPPDMVRLGARQL--NETSATQQDIKILIIVLHPKYR 276
                :.|||:|:||.:|||||||.:....||..||:|...|  .:.|...|.::|..:..||.|:
  Fly   172 ----YKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYK 232

  Fly   277 SSAYYHDIALLKLTRRVKFSEQVRPACLWQLPELQIPTVVAAGWGRTEFLGAKSNALRQVDLDVV 341
            ...||.|||||||.:.|:.:|.|||..||..|||......|.|:|.|.|....:|.|..::|.||
  Fly   233 KKMYYDDIALLKLEKEVELTEYVRPVRLWVFPELPTTIAFAMGYGATSFAKPMTNRLTNLNLTVV 297

  Fly   342 PQMTCKQIYRKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGGPIHALLP--------EYNCVAFV 398
            |...|..........|.|::|.|.||......|||||||||||:...||        .|:    :
  Fly   298 PNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYH----L 358

  Fly   399 VGITSFGKFCAAPNAPGVYTRLYSYLDWIE 428
            :||||:|.||.: :.|.||||:.|:|||||
  Fly   359 IGITSYGVFCRS-SYPSVYTRVSSFLDWIE 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	104/253 (41%)
		Tryp_SPc	186..427	CDD:214473	101/250 (40%)
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	103/261 (39%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	102/260 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0012732
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.910