DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and CG18180

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_648341.1	Gene:	CG18180 / 39125	FlyBaseID:	FBgn0036024	Length:	264	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	72/250 - (28%)
Similarity:	109/250 - (43%)	Gaps:	37/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 IVGGTPTRHGLFPHMAALG-WTQGSGSKDQDIKWGCGGA--LVSELYVLTAAHCATSGSKPPDMV 247
            ||.|.|...|..|::..|. .|.||.|       |..||  :::..::||||||.|.     |.|
  Fly    36 IVNGYPAPEGKAPYIVGLFIRTDGSNS-------GAVGAGTIIANDWILTAAHCLTG-----DYV 88

  Fly   248 RLG-ARQLNETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVR----PACLWQL 307
            .:. ........|.:|.::....:.||.:.|.. ..||.|:: |..|.|:..:.    |:...|.
  Fly    89 EIHYGSNWGWNGAYRQTVRRDNFISHPDWPSQG-GRDIGLIR-TPHVDFNGLINKIPLPSMNEQN 151

  Fly   308 PELQIPTVVAAGWGRTEFLGAKSNALRQVDLDVVPQMTCKQIYRKERRLPRGIIEGQFCAGYLPG 372
            ...|....||.|||..: .|..::.|:.||:.::....|:|.|       ..:.....|..: ..
  Fly   152 DRYQDTWCVACGWGGMD-NGNLADWLQCVDVQIISNSECEQAY-------GSVASTDMCTRH-AD 207

  Fly   373 GRDTCQGDSGGPIHALLPEYNCVAFVVGITSFGKFCAAPNAPGVYTRLYSYLDWI 427
            |:..|.||||||   |:...|  |.:||:.:|.. .:..:.|..|||:..||:||
  Fly   208 GKSVCGGDSGGP---LVTHDN--ARLVGVITFAS-VSCHDGPSGYTRVSDYLEWI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	71/249 (29%)
		Tryp_SPc	186..427	CDD:214473	70/248 (28%)
CG18180	NP_648341.1	Tryp_SPc	35..256	CDD:214473	70/248 (28%)
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	71/249 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436984
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940