DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and CG8329

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_648339.1	Gene:	CG8329 / 39123	FlyBaseID:	FBgn0036022	Length:	259	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	79/308 - (25%)
Similarity:	115/308 - (37%)	Gaps:	74/308 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 LADKHVLAQRISATKCQEYNAAARRLHLTDTGRTFSGKQCVPSVPLIVGGTPTRHGLFPHMAALG 204
            ::.|.||.....||.|...|.       ..|.....|.:     .:||.|.|...|..|:...|.
  Fly     1 MSKKLVLLLLFVATVCAHRNR-------NRTAHHGGGPK-----DIIVNGYPAYEGKAPYAVGLR 53

  Fly   205 WTQGSGSKDQDIKWGCGGALVSELYVLTAAHCATSGSKPPDMVRLGAR-----QLNETSATQQDI 264
            ...|:..         ||:::...:|||||||.|:.|.   .:..|:.     ||..|.......
  Fly    54 MNNGAVG---------GGSVIGNNWVLTAAHCLTTDSV---TIHYGSNRAWNGQLQHTVNKNNFF 106

  Fly   265 KILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACL-------------WQLPELQIPTVV 316
            :      ||.|.:|| .|||.|:: |..|.|:..:....|             |         .|
  Fly   107 R------HPGYPNSA-GHDIGLIR-TPYVSFTNLINKVSLPKFSQKGERFENWW---------CV 154

  Fly   317 AAGWGRTEFLGAKSNALRQVDLDVVPQMTCKQIYRKERRLPRGIIEGQFCAGYLPGGRDTCQGDS 381
            |.|||... .|..::.|:.:|:.|:....|.:.|        |.:...........|:..|.|||
  Fly   155 ACGWGGMA-NGGLADWLQCMDVQVISNGECARSY--------GSVASTDMCTRATDGKSVCGGDS 210

  Fly   382 GGPIHALLPEYNCVAFVVGITSFGKFCAAPNAPGVYTRLYSYLDWIEK 429
            ||   ||:...|.:.  ||:.:|... ...:.|..|||:..:||||.:
  Fly   211 GG---ALVTHDNPIQ--VGVITFASI-GCKSGPSGYTRVSDHLDWIRE 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	70/262 (27%)
		Tryp_SPc	186..427	CDD:214473	68/258 (26%)
CG8329	NP_648339.1	Tryp_SPc	35..253	CDD:238113	70/262 (27%)
CG8329	NP_648339.1	Tryp_SPc	35..250	CDD:214473	68/258 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030