DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment snk and Hayan

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001097020.1	Gene:	Hayan / 32831	FlyBaseID:	FBgn0030925	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	439	Identity:	123/439 - (28%)
Similarity:	190/439 - (43%)	Gaps:	90/439 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LHLI---LQTPNLEALDALEI-INYQTTKYTIPEVWKEQ------PVATIGEDVDDQDTEDEESY 70
            :||:   |:...::...|.|: :..|||....|.....|      |....|:| .|:||:.:|.:
  Fly   262 IHLVNDRLREQGMQIEPAREVPMVLQTTPTPTPAPTPTQLIDPFEPYRFRGQD-RDKDTQPQEPW 325

  Fly    71 LKFGDDAEVRTSVSEGLHEGAFCRRSFDGRSGYCILAYQCLHVIREYRVHGTRIDICTHRNNVPV 135
            ....::.:...:.|                            :........|..:....|.|:|
  Fly   326 NDVSNNLDADPAPS----------------------------IFNPAETRPTTPNPNPSRVNLP- 361

  Fly   136 ICCPLADKHVLAQRISATKCQEYNAAARRL--HLTDTGRTFSGKQCVPSVPLIVGGTPTRHGLFP 198
                  :|    :|.|...|::..:..:.|  |:.|                   |.....|::|
  Fly   362 ------EK----ERPSVAACEKIRSGGKPLTVHILD-------------------GERVDRGVYP 397

  Fly   199 HMAALGWTQ-GSGSKDQDIKWGCGGALVSELYVLTAAHCATSGSKPPDMVRLGARQLNETSATQQ 262
            ||||:.:.. ||.:      :.|||:|::..:|||||||..|....|..|||||..:.......|
  Fly   398 HMAAIAYNSFGSAA------FRCGGSLIASRFVLTAAHCVNSDDSTPSFVRLGALNIENPEPGYQ 456

  Fly   263 DIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPELQIPTV----VAAGWGRT 323
            ||.::.:.:||.|..|:.|:|||:|:|....|.|:.:|||||:  .:...|..    ..||||..
  Fly   457 DINVIDVQIHPDYSGSSKYYDIAILQLAEDAKESDVIRPACLY--TDRSDPPANYKYFVAGWGVM 519

  Fly   324 EFLG-AKSNALRQVDLDVVPQMTCKQIYRKE----RRLPRGIIEGQFCAGYLPGGRDTCQGDSGG 383
            .... |.|..|.:..||:||...|...:.::    |.|.||:|..|.||......:|.|||||||
  Fly   520 NVTNRAVSKILLRAALDLVPADECNASFAEQPSANRTLRRGVIASQLCAADKNQRKDACQGDSGG 584

  Fly   384 PIHALLPEYNCVAFVVGITSFGKFCAAPNAPGVYTRLYSYLDWIEKIAF 432
            |:...:.:.:....:||:.|.|..||. ..||:|||:.|:||:||.|.:
  Fly   585 PLILEIDDVDGTYSIVGVISSGFGCAT-KTPGLYTRVSSFLDYIEGIVW 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829	4/45 (9%)
		Tryp_SPc	186..430	CDD:238113	93/253 (37%)
		Tryp_SPc	186..427	CDD:214473	91/250 (36%)
Hayan	NP_001097020.1	CLIP	32..80	CDD:197829
		Tryp_SPc	384..627	CDD:214473	93/270 (34%)
		Tryp_SPc	385..630	CDD:238113	94/272 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950