DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and sphe

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_573148.2	Gene:	sphe / 32648	FlyBaseID:	FBgn0030774	Length:	249	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	68/221 - (30%)
Similarity:	106/221 - (47%)	Gaps:	31/221 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 CGGALVSELYVLTAAHCATSGSKPPDMVRLGARQLNETS--ATQQDIKILIIVLHPKYRSSAYYH 282
            |||:::|:..:||.|||.....|..|..||..| :..|:  |..:.:.:..:.:||.|.:  ..:
  Fly    51 CGGSILSQTKILTTAHCVHRDGKLIDASRLACR-VGSTNQYAGGKIVNVESVAVHPDYYN--LNN 112

  Fly   283 DIALLKLTRRVKFSEQVRPACLWQLPELQIPT----VVAAGWGRTEFLGAKSNALRQVDLDVVPQ 343
            ::|::.|:..:.:::::....|....| .:|.    |:.||||||.. |..|..:||:.|.|.|:
  Fly   113 NLAVITLSSELTYTDRITAIPLVASGE-ALPAEGSEVIVAGWGRTSD-GTNSYKIRQISLKVAPE 175

  Fly   344 MTCKQIYRKERRLPRGIIEGQFCAGY-LPGGRDTCQGD-SGGPIHALLPEYNCVAFVVGITSFGK 406
            .||...|....       |..||..: |..|  ||.|| .||.|:.        ..::|:|:|..
  Fly   176 ATCLDAYSDHD-------EQSFCLAHELKEG--TCHGDGGGGAIYG--------NTLIGLTNFVV 223

  Fly   407 FCAAPNAPGVYTRLYSYLDWI-EKIA 431
            .......|.|:.||.||.||| |:||
  Fly   224 GACGSRYPDVFVRLSSYADWIQEQIA 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	66/218 (30%)
		Tryp_SPc	186..427	CDD:214473	63/214 (29%)
sphe	NP_573148.2	Tryp_SPc	42..247	CDD:238113	65/217 (30%)
sphe	NP_573148.2	Tryp_SPc	42..244	CDD:214473	63/214 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930