DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and sphinx1

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_729255.2	Gene:	sphinx1 / 318005	FlyBaseID:	FBgn0052383	Length:	253	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	53/289 - (18%)
Similarity:	104/289 - (35%)	Gaps:	104/289 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 PLIVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTA----------AHCAT 238
            |.|.||...:.....::..:.:.:   |:...:.:| .|.::|..::||.          .|.|:
  Fly    24 PRIAGGYRAKTFTIIYLVGIVYFK---SQTSSLNYG-AGTIISNQWILTVKTVLKYSYIEVHLAS 84

  Fly   239 SGS-KPPDMVRLGARQLNETSATQQDIKILIIVLHPKYRSSAYY-----HDIALLKLTRRVKFSE 297
            ..| :..|::|:                         |:.:..:     |.|||:|...: ||..
  Fly    85 RRSYRGFDIIRI-------------------------YKENFRFHYDNDHVIALVKCPYQ-KFDR 123

  Fly   298 QVRPACLWQLPELQIPT------------VVAAGWGRTEFLGAK-SNALRQVDLDVVPQMTCKQI 349
                    ::..:::|.            .:..|:| ||...|| ...:|.::::|:....|.:.
  Fly   124 --------RMDRVRVPAYDTRFERYVGNMTMVCGYG-TEKRHAKLPEWMRCIEVEVMNNTECAKY 179

  Fly   350 YRKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGGPIHA------------LLPEYNCVAFVVGIT 402
            |...:..       :.|... .|.:..|:||.||.:..            |:|| ||
  Fly   180 YTPLKWY-------EMCTSG-EGFKGVCEGDIGGAVVTMGPNPTFIGIIWLMPE-NC-------- 227

  Fly   403 SFGKFCAAPNAPGVYTRLYSYLDWIEKIA 431
            |.|       .|.|:.|:..::.||::::
  Fly   228 SIG-------YPSVHIRVSDHIKWIKRVS 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	52/284 (18%)
		Tryp_SPc	186..427	CDD:214473	50/281 (18%)
sphinx1	NP_729255.2	Tryp_SPc	25..245	CDD:214473	50/282 (18%)
sphinx1	NP_729255.2	Tryp_SPc	26..248	CDD:304450	52/284 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437052
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030