DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and spirit

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	146/417 - (35%)
Similarity:	201/417 - (48%)	Gaps:	65/417 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LHLILQTPNLEALDALEIINYQTTKYTIPEVWKEQPVATIGEDVDDQDTEDEESYLKFGDDAEVR 80
            |||:|.:..|.|:.|...|:.|:.:..|      .||.|.    |:...||           ..|
  Fly    15 LHLLLVSLPLLAVHATPAISPQSLRGII------FPVETF----DECQLED-----------VAR 58

  Fly    81 TSVSEGLHEGAFCRRSFDGRSGYCILAYQCLHVIREYRVHGTRIDICTHRNNVPVICCPLADKHV 145
            |.        ..|||..|           |...:..:.........|........:||..|...:
  Fly    59 TK--------GTCRRMED-----------CPSALNGWLERRESPKTCYFVRFDHYVCCAPAVAPI 104

  Fly   146 LAQRISATKCQEYNAAARRLHLTDTGRTFSGKQCVPSVPLIVGGTPTRHGLFPHMAALGWTQGSG 210
            :. |.|...|.|.|..::   :.:....|..         :|||.|||...||.||||||   ..
  Fly   105 VT-RSSQQACNELNKVSK---VKEIDEFFVS---------VVGGMPTRPREFPFMAALGW---RS 153

  Fly   211 SKDQDIKWGCGGALVSELYVLTAAHCATSGSKPPDMVRLGARQLNETSATQQDIKILIIVLHPKY 275
            :.||.|.:.|||||::..:||||||||..|.:||..||||...|..|..  :||.|..:::||.|
  Fly   154 NFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGDNLTLTEG--EDISIRRVIIHPDY 216

  Fly   276 RSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPELQIPTVVAAGWGRTEFLGAKSNALRQVDLDV 340
            .:|..|:|||||:|....|  .:::|.|:|...|:....|.|.|:|:|.|.|..|..|.:|.|..
  Fly   217 SASTAYNDIALLELETAAK--PELKPTCIWTQKEVTNTLVTAIGYGQTSFAGLSSAQLLKVPLKS 279

  Fly   341 VPQMTCKQIYRKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGGPIHALLPEYNCVAFVVGITSFG 405
            |....|:..|:|: :|.:|::..|.|||.:.|.|||||||||||   ||.:...:.:||||||.|
  Fly   280 VSNEECQHHYQKD-QLAQGVLGTQMCAGDITGERDTCQGDSGGP---LLMQDGLLGYVVGITSLG 340

  Fly   406 KFCAAPNAPGVYTRLYSYLDWIEKIAF 432
            :.||: ..|.||||:.|::||||.|.:
  Fly   341 QGCAS-GPPSVYTRVSSFVDWIEGIVW 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829	7/45 (16%)
		Tryp_SPc	186..430	CDD:238113	112/243 (46%)
		Tryp_SPc	186..427	CDD:214473	109/240 (45%)
spirit	NP_001162707.1	CLIP	51..98	CDD:197829	11/76 (14%)
		Tryp_SPc	132..364	CDD:238113	112/243 (46%)
		Tryp_SPc	132..361	CDD:214473	109/240 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450024
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	1	1.000	-	-		FOG0012732
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950