DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and CG18420

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_995715.1	Gene:	CG18420 / 2768924	FlyBaseID:	FBgn0028866	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	86/281 - (30%)
Similarity:	123/281 - (43%)	Gaps:	53/281 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 FSGKQCVPSVPL-----IVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTA 233
            |...:|....||     ||.|........|.||.|     ..|.:|.|   |||.|:|...||||
  Fly    26 FLDSECGTRSPLKLGPRIVNGKVAVRNSSPWMAFL-----HTSSNQFI---CGGTLISRRLVLTA 82

  Fly   234 AHCATSGSKPPDMVRLGA--------RQLNETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLT 290
            |||....:  ..:||||.        |:.::.:.|.|         |..|..:.:.:|||||:|.
  Fly    83 AHCFIPNT--TIVVRLGEYNRKLKGYREEHQVNRTFQ---------HRFYDPNTHANDIALLRLV 136

  Fly   291 RRVKFSEQVRPACL-----WQLPELQIPTVVAAGWGRTEFLGAKSNALRQVDLDVVPQMTCKQIY 350
            ..|.:...:||.|:     |:.....|..:...||||||.: ..|:.||.:|:...|...|..
  Fly   137 SNVVYKANIRPICIMWDASWKHHIDSIKVLTGTGWGRTESM-HDSSELRTLDISRQPSKMCAF-- 198

  Fly   351 RKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGGPIHALLPEYNCVAFV-VGITSFGKFCAAPNAP 414
                   ..::..|||||  ....:.|.||:|||:.|::...|...|| |||....|.|   ..|
  Fly   199 -------GSVLSNQFCAG--NWNSNLCIGDTGGPVGAMVRYRNAFRFVQVGIAITNKRC---QRP 251

  Fly   415 GVYTRLYSYLDWIEKIAFKQH 435
            .|:|.:.|::::|.:|...|:
  Fly   252 SVFTDVMSHIEFIRRIFLTQN 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	80/257 (31%)
		Tryp_SPc	186..427	CDD:214473	79/254 (31%)
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	79/255 (31%)
CG18420	NP_995715.1	Tryp_SPc	43..267	CDD:238113	80/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940