DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and CG30090

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_725487.1	Gene:	CG30090 / 246448	FlyBaseID:	FBgn0050090	Length:	291	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	88/267 - (32%)
Similarity:	122/267 - (45%)	Gaps:	52/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 IVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTAAHCATSGSKPPDMVRLG 250
            |:||........|.||.:         ...:|..|||.|:::.:|||||||...||..  .||||
  Fly    40 IIGGRDAIINSNPWMAYI---------HSSVKLICGGTLITQRFVLTAAHCVNEGSAV--KVRLG 93

  Fly   251 ARQLNETSATQQDIKILI----------IVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACL- 304
              :.::|:....:.||.|          ...|.|:......:|||||:|.:.|.|...:.|.|:
  Fly    94 --EYDDTATEDCNSKICIPRAEEHDVDMAFRHGKFSEIKNLNDIALLRLAKFVTFKAHISPICII 156

  Fly   305 --WQLPEL--QIPTVVAAGWGRTEFLGAKSNALRQVDLDVVPQMTCKQIYRKE---RRLPRGIIE 362
              ....||  .|...||.|||.|     :::..|.     |.|:|..|.|...   :.|.|.:.:
  Fly   157 LGTSKRELVDSIEWFVATGWGET-----RTHRTRG-----VLQITQLQRYNSSQCMQALGRLVQQ 211

  Fly   363 GQFCAGYLPGGRDTCQGDSGGPIHAL---LPEYNCVAFVVGITSFG-KFCAAPNAPGVYTRLYSY 423
            .|.|||.|  |.|||.||||||:...   :.:...|.|  |:.|:| :.|   :..||||.:|||
  Fly   212 NQICAGRL--GSDTCNGDSGGPLFQTVRHMDKMRPVQF--GVVSYGSREC---SGIGVYTDVYSY 269

  Fly   424 LDWIEKI 430
            .|||..:
  Fly   270 ADWIATV 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	88/265 (33%)
		Tryp_SPc	186..427	CDD:214473	86/262 (33%)
CG30090	NP_725487.1	Tryp_SPc	39..273	CDD:214473	86/262 (33%)
CG30090	NP_725487.1	Tryp_SPc	40..276	CDD:238113	88/265 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437451
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940