DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and Plau

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_032899.1	Gene:	Plau / 18792	MGIID:	97611	Length:	433	Species:	Mus musculus

Alignment Length:	370	Identity:	100/370 - (27%)
Similarity:	156/370 - (42%)	Gaps:	82/370 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 SVSEGLHEGAFCRRSFDGRSGYCILAYQCLHVIREYRVHGTRIDICTHRNNVPVICCPLADKHVL 146
            ::|.||.:..:||...:.:..:|.:.......::|..||.                |.|:.|...
Mouse   112 AISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMVHD----------------CSLSKKPSS 160

  Fly   147 AQRISATKCQEYNAAARRLHLTDTGRTFSGKQCVPSVPLIVGGTPTRHGLFPHMAALGWTQGSGS 211
            :......:|                    |::.:.....||||..|.....|..||: :.:..|.
Mouse   161 SVDQQGFQC--------------------GQKALRPRFKIVGGEFTEVENQPWFAAI-YQKNKGG 204

  Fly   212 KDQDIKWGCGGALVSELYVLTAAHCATSGSKPPD-MVRLGARQLNETSATQQDIKILI--IVLHP 273
            .....|  |||:|:|..:|.:||||.....|..: :|.||  |..|:|....::|..:  ::||.
Mouse   205 SPPSFK--CGGSLISPCWVASAAHCFIQLPKKENYVVYLG--QSKESSYNPGEMKFEVEQLILHE 265

  Fly   274 KYR--SSAYYHDIALLKLT----RRVKFSEQVRPACLWQLPELQIPTVVAA---------GWGR- 322
            .||  |.||::||||||:.    :..:.|..::..|   ||    |....|         |:|:
Mouse   266 YYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTIC---LP----PRFTDAPFGSDCEITGFGKE 323

  Fly   323 --TEFLGAKSNALRQVDLDVVPQMTCKQ--IYRKERRLPRGIIEGQFCAGYLPGGRDTCQGDSGG 383
              :::|..|:  |:...:.:|....|.|  .|..|      |.....||.......|:|:|||||
Mouse   324 SESDYLYPKN--LKMSVVKLVSHEQCMQPHYYGSE------INYKMLCAADPEWKTDSCKGDSGG 380

  Fly   384 PIHALLPEYNCVAFVVGITSFGKFCAAPNAPGVYTRLYSYLDWIE 428
            |   |:........:.||.|:|:.||..|.||||||:..:||||:
Mouse   381 P---LICNIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLDWIQ 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829	6/45 (13%)
		Tryp_SPc	186..430	CDD:238113	86/266 (32%)
		Tryp_SPc	186..427	CDD:214473	84/263 (32%)
Plau	NP_032899.1	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	35..58
		Kringle	71..152	CDD:333799	9/55 (16%)
		Connecting peptide	153..179		4/45 (9%)
		Tryp_SPc	180..424	CDD:238113	86/266 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960