DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and try-3

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_001367393.1	Gene:	try-3 / 183420	WormBaseID:	WBGene00006621	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	270	Identity:	72/270 - (26%)
Similarity:	106/270 - (39%)	Gaps:	69/270 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 GSGSKDQDIKWG--------------CGGALVSELYVLTAAHCATSGSKPPDMVRLGARQL---- 254
            |..|.|....|.              ||..::.:.:::||||||         ::|..|..
Worm    40 GGNSIDDGANWMAKLVSYGDNGQGILCGATVIDDFWLVTAAHCA---------LQLQTRSFVYVR 95

  Fly   255 NETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPE---LQIPTVV 316
            ...:..::...:....:|..|.:....:|||||:::..:. ...::|.||.....   .|....|
Worm    96 EPKNNRERSFSVKEAYIHSGYNNQTADNDIALLRISSDLS-KLGIKPVCLVHDDSKLLKQYKNGV 159

  Fly   317 AAGWGRTEFLG---------AKSNALRQVDLDVVPQMTCKQIYRKERRLPRGIIEGQFCAG-YLP 371
            ..|:|.|  ||         ..|..|:...:.::....|.:.:|....|...|...|.||| ||.
Worm   160 VIGYGLT--LGEDSSGEPKLINSQTLQSTSVPIISDDDCVKTWRFLSLLSVKITGYQICAGAYLH 222

  Fly   372 GGRDTCQGDSGGP--IHALLPEYNCVAFVVGITSF-----------GKFCAAPNAPGVYTRLYSY 423
            |   |..||||||  ||....||    ..:||||:           |||      ||||||:..|
Worm   223 G---TAPGDSGGPLLIHKSNGEY----VQIGITSYGADGLDGVIDQGKF------PGVYTRISKY 274

  Fly   424 LDWIEKIAFK 433
            :.||:.:..|
Worm   275 VPWIQGVIGK 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	71/265 (27%)
		Tryp_SPc	186..427	CDD:214473	69/262 (26%)
try-3	NP_001367393.1	Tryp_SPc	38..279	CDD:238113	70/263 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010