DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snk and Gzmk

DIOPT Version :9

Sequence 1:	NP_001097766.1	Gene:	snk / 41607	FlyBaseID:	FBgn0003450	Length:	435	Species:	Drosophila melanogaster
Sequence 2:	NP_032222.1	Gene:	Gzmk / 14945	MGIID:	1298232	Length:	263	Species:	Mus musculus

Alignment Length:	255	Identity:	78/255 - (30%)
Similarity:	118/255 - (46%)	Gaps:	31/255 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 IVGGTPTRHGLFPHMAALGWTQGSGSKDQDIKWGCGGALVSELYVLTAAHCAT---SGSKPPDMV 247
            |:||...:....|.||::.:..         |..|||.|:...:|||||||.:   .|..|  .|
Mouse    26 IIGGREVQPHSRPFMASIQYRS---------KHICGGVLIHPQWVLTAAHCYSWFPRGHSP--TV 79

  Fly   248 RLGARQLNETSATQQDIKILIIVLHPKYRSSAYYHDIALLKLTRRVKFSEQVRPACLWQLPELQI 312
            .|||..|::....:|..:|...:...:.:|.:..|||.|:||....:.::.|:...|.....|:.
Mouse    80 VLGAHSLSKNEPMKQTFEIKKFIPFSRLQSGSASHDIMLIKLRTAAELNKNVQLLHLGSKNYLRD 144

  Fly   313 PT-VVAAGWGRT--EFLGAKSNALRQVDLDVVPQMTC-KQIYRKERRLPRGIIEGQFCAGYLPGG 373
            .| ....|||.|  :.|.| |:.||:|.:.::.:..| .|.|...:.:   |.:...|||...|.
Mouse   145 GTKCQVTGWGTTKPDLLTA-SDTLREVTVTIISRKRCNSQSYYNHKPV---ITKDMICAGDARGQ 205

  Fly   374 RDTCQGDSGGPIHALLPEYNCVAFVVGITSFGKFCAAPNAPGVYTRL-YSYLDWIE-KIA 431
            :|:|:||||||:       .|......:.|.|..|.....||:||.| ..|..||: |:|
Mouse   206 KDSCKGDSGGPL-------ICKGIFHALVSQGYKCGIAKKPGIYTLLTKKYQTWIKSKLA 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snk	NP_001097766.1	CLIP	93..139	CDD:197829
		Tryp_SPc	186..430	CDD:238113	76/252 (30%)
		Tryp_SPc	186..427	CDD:214473	74/248 (30%)
Gzmk	NP_032222.1	Tryp_SPc	25..253	CDD:214473	74/248 (30%)
Gzmk	NP_032222.1	Tryp_SPc	26..256	CDD:238113	76/251 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D476534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010